Results 11 to 20 of about 189,073 (267)

Addressing Technology Uncertainties in Power Plants with Post-Combustion Capture

open access: yes, 2012
Risks associated with technology, market and regulatory uncertainties for First-Of-A-Kind fossil power generation with CCS can be mitigated through innovative engineering approaches that will allow solvent developments occurring during the early stage of
Gibbins, Jon   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CO2 Highways for Europe: Modelling a Carbon Capture, Transport and Storage Infrastructure for Europe. CEPS Working Document No. 340/November 2010 [PDF]

open access: yes, 2010
This paper presents a mixed integer, multi-period, cost-minimising model for a carbon capture, transport and storage (CCTS) network in Europe. The model incorporates endogenous decisions about carbon capture, pipeline and storage investments. The capture,
Tissen, Andreas.   +9 more
core  

Instantaneous Capture and Mineralization of Flue Gas Carbon Dioxide: Pilot Scale Study

open access: yes, 2010
Multiple CO2 capture and storage (CCS) processes are required to address anthropogenic CO2 problems. However, a method which can directly capture and mineralize CO2 at a point source, under actual field conditions, has advantages and could help offset ...
Pradip Bhattacharyya   +8 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Process engineering and development of post-combustion CO2 separation from fuels using limestone in CaO-looping cycle [PDF]

open access: yes, 2011
Global CO2 emissions produced by energy-related processes, mainly power plants, have increased rapidly in recent decades; and are widely accepted as the dominant contributor to the greenhouse gas (GHG) effect and consequent climate changes.
Kavosh, Masoud
core  

Mass transfer and hydrodynamic characteristics of new carbon carbon packing: Application to CO2 post-combustion capture [PDF]

open access: yes, 2011
A novel structured packing, the 4D packing, has been characterized in terms of hydrodynamics, effective area and gas side mass transfer coefficient. The increase of the 4D opening fraction allows to reduce pressure drop and to get a better capacity than ...
Prevost, Michel   +11 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

The Effects of Different Dopants and Doping Procedures on the Reactivity of CaO-based Sorbents for CO2 Capture [PDF]

open access: yes, 2012
Calcium-looping technology is a promising CO2-capture technology. The economics and environmental impact of the process are affected by the rapid decay in reactivity of the limestone sorbent, which necessitates a high purge rate from the system to ...
Al-Jeboori, Mohamad J   +3 more
core   +1 more source

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