Results 71 to 80 of about 4,623,074 (340)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

CO2 Highways for Europe: Modelling a Carbon Capture, Transport and Storage Infrastructure for Europe. CEPS Working Document No. 340/November 2010 [PDF]

open access: yes, 2010
This paper presents a mixed integer, multi-period, cost-minimising model for a carbon capture, transport and storage (CCTS) network in Europe. The model incorporates endogenous decisions about carbon capture, pipeline and storage investments. The capture,
Tissen, Andreas.   +9 more
core  

Thermochemistry of a Biomimetic and Rubisco-Inspired CO2 Capture System from Air

open access: yesC, 2016
In theoretical studies of chemical reactions the reaction thermochemistry is usually reported for the stoichiometric reaction at standard conditions (ΔG°, ΔH°, ΔS°). We describe the computation of the equilibrium concentrations of the CO2-adducts for the
Andrew Muelleman   +3 more
doaj   +1 more source

Integrated CO2 capture and utilization with CaO-alone for high purity syngas production

open access: yesCarbon Capture Science & Technology, 2021
Carbon capture and utilization (CCU) represent a promising strategy to reduce CO 2 emissions and promote a sustainable economy. We report an integrated CCU (ICCU) process by integrating CO 2 capture with reverse water gas shift reaction by applying ...
Shuzhuang Sun   +5 more
semanticscholar   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Aerosol emissions and mitigation of aqueous AMP/PZ solvent for postcombustion CO2 capture

open access: yesCarbon Capture Science & Technology
Aerosol emissions from the CO2-capture process have a significant impact on both solvent depletion and environmental contamination. This work comprehensively investigated the emissions of AMP (2-amino-2-methyl-1propanol)/PZ (piperazine) from a bench ...
Lianbo Liu   +4 more
doaj   +1 more source

A new relevant membrane application: CO2 direct air capture (DAC)

open access: yesChemical Engineering Journal, 2022
Since carbon dioxide (CO2) is the primary greenhouse gas emitted due to human activities into the atmosphere, strong research efforts have been developed towards capturing and 2 decreasing its production.
Roberto Castro-Muñoz   +3 more
semanticscholar   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Experimental validation and multi-criteria decision optimization of parameters in gas hydrate-based desalination

open access: yesSouth African Journal of Chemical Engineering
Gas hydrate-based desalination (GHBD) is a promising technology for sustainable water treatment, yet its practical implementation is often hindered by the slow kinetics and complexity of optimizing multiple process parameters.
Sirisha Nallakukkala   +4 more
doaj   +1 more source

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