Results 171 to 180 of about 429,154 (315)

Characterization of discontinuous ventilation cycles in nymphal Ixodes scapularis. [PDF]

PLoS One
Schofield S, Waters JS, D Y Bandara YMN, Couret J.   +3 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

A MEMS Microbolometer-Based ATR Mid-Infrared Sensor for Direct Dissolved CO₂ Detection and UV-Induced Sediment Carbon Assay in Aquatic Environments. [PDF]

Sensors (Basel)
Hasan MR, Nikeghbal A, Tran S, Sium FS, Noh S, Kim H, Mastrangelo CH.   +6 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Establishment of a Purge and Trap Continuous-Flow Isotope Ratio Mass Spectrometer System for Analysis of Stable Nitrate Isotopes (δ¹⁵N and δ¹⁸O) in Water Samples by Ti(III) Reduction. [PDF]

Rapid Commun Mass Spectrom
Gcakasi MN, Stumpp C, Watzinger A.
europepmc   +1 more source

Is Bedside End-Tidal CO₂ Measurement a Screening Tool to Exclude Pulmonary Embolism in Emergency Department? [PDF]

J Clin Med Res, 2019
Ozdemir M, Sonmez BM, Yilmaz F, Yilmaz A, Duyan M, Komut S.   +5 more
europepmc   +1 more source

Raman Spectral Shifts of CO2 as Measure of CO2-philicity of Solutes in Supercritical CO2

Raman Spectral Shifts of CO2 as Measure of CO2-philicity of Solutes in Supercritical CO2
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

The French-German Climate Monitoring Initiative on global observations of atmospheric CH4

, 2010
Knowledge of concentrations and fluxes of the most important long-lived greenhouse carbon dioxide (CO2) and methane (CH4) is a key element of climate change research.
Gibert, Fabien, Kiemle, Christoph, Flamant, Pierre, Fabien, Gibert, Fix, Andreas, Ciais, Philippe, Quatrevalet, Mathieu, Amediek, Axel, Ehret, Gerhard, Wirth, Martin   +9 more
core  

Ovoid cell is an inducible small-sized morphotype that enhances proliferation and antifungal drug tolerance in the human fungal pathogen Cryptococcus neoformans. [PDF]

PLoS Pathog
Zhang X, Shu X, Liu Y, Zhao Y, Chen H, Xiong F, Kang M, Cao C.   +7 more
europepmc   +1 more source