Results 61 to 70 of about 1,641,615 (299)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A review on recent developments in N-methylation using CO2

, 2021
Owing to the increasing emissions of carbon dioxide (CO2) in recent years, people's interest in the use of CO2, especially the synthesis of value-added chemicals with CO2 as a C1 blocking, has also increased year by year. In particular, the N-methylation
Lin, Shanshan, Liu, Jianguo, Jianguo Liu, Ma, Longlong, Shanshan Lin, Longlong Ma   +5 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

New possibility for PET plastic recycling by a tailored hydrolytic enzyme

Green Energy & Environment
Plastic waste puts a huge burden on the ecosystem due to the current lack of mature recycling technology. Poly (ethylene terephthalate) (PET) is one of the most produced plastics in the world.
Shijie Yu, Qinghai Li, Yanguo Zhang, Hui Zhou   +3 more
doaj   +1 more source

High-temperature thermal manipulator using thermal metamaterials based on transformation thermodynamics

AIP Advances, 2018
A thermal manipulator for use in high temperature environments was designed and constructed based on the coordinate transformation method of transformation thermodynamics.
G. Y. Huang, J. F. Liu, T. R. Fu, Y. M. Zhao, S. Lu, B. Liu   +5 more
doaj   +1 more source

Conceptualization and process simulation of a CO2-based methanol production plant [PDF]

Chemical Industry and Chemical Engineering Quarterly
The present study conceptualizes and simulates a methanol production process through the direct hydrogenation of captured CO2. CuO/ZnO/ZrO2 was employed as the catalyst and Aspen HYSYS was used for the process simulation.
Khawaja Saman, Usman Muhammad Rashid, Aslam Rabya   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Cell-nanoparticle assembly fabricated for CO2 capture and in situ carbon conversion

, 2016
Some microorganisms can selectively capture carbon dioxide without light irradiation, which proposes a wide application prospect. The purpose of this study was to create a microorganism-nanoparticle assembly, which will be used for carbon dioxide ...
Li, Qiang, Zhao, Lan, Wu, Dexi, Qiu, Han, Wang, Dan, Gong, Fangling, Li, Liang, Zhang, Rongyue, Ma, Guanghui, Huang, Yongdong   +9 more
core   +1 more source

Effect of MgAl2O4 catalyst support synthesis method on the catalytic activity of nickel Nano catalyst in reverse water gas shift reaction [PDF]

Iranian Journal of Chemical Engineering, 2019
In this research effect of synthesis method of magnesium aluminate as support of Ni catalysts at the reverse water gas shift (RWGS) reaction was evaluated.
A. Ranjbara, F. Aghamiri, A. Irankhah
doaj