Results 71 to 80 of about 48,165 (269)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The coaching approach to the disclosing and improving of the future pre-school teachers’ speech potential

Науковий Вісник Південноукраїнського Національного Педагогічного Університету імені К. Д. Ушинського, 2019
The article is devoted to the problem of using innovative technologies in professional speech activities aimed at the future educators of preschool education institutions, namely, coach-technologies.
Rudenko Yuliia
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

EXPERIMENTAL DETERMINATION OF THE HYDROGEN CONCENTRATION IN THE BATTERY BOXES OF THE PASSENGER CARS

Nauka ta progres transportu, 2010
In the work the experimental determination of the hydrogen concentration in accumulator boxes of the coach in a charging mode of nickel-cadmium batteries in operating conditions (stop and operation) is presented.
G. S. Ighnatov, V. R. Raspopin, S. D. Sychev, S. V. Shmakov, P. A. Khozja, A. A. Sulim, A. A. Melnyk   +6 more
doaj  

Mindfulness in coaching: A model for coaching practice

The Coaching Psychologist, 2017
This is the first in a series of papers to look at mindfulness coaching as an approach suitable for use with coaching clients. This paper presents a brief overview of mindfulness for readers who are less familiar with the approach and highlights other sources for a fuller account of mindfulness coaching. The paper sets the scene for a subsequent series
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Contributions to the Definition of the Managerial Profiles [PDF]

Theoretical and Applied Economics, 2008
Considering that the superior manager variety is a result of the different levels of “accommodation” of the characteristics met in the dedicated literature, in the beginning we have summed up the opinions of the subjects of a statistical research in some
Dan Constantinescu
doaj  

Quality Coaching, Learning and Coach Development

Japanese Journal of Sport Education Studies, 2011
Performance coaches are the architects of the coaching environment and responsible for leading and managing the coach-athlete-performance relationship. The effectiveness of the coach in leading and managing this relationship is important for producing appropriate outcomes such as physical and psycho-social development as well as competition results ...
openaire   +3 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source