Results 241 to 250 of about 3,265,974 (326)

From Droplet to Diagnosis: Spatio‐Temporal Pattern Recognition in Drying Biofluids

Advanced Intelligent Systems, EarlyView.
This article integrates machine learning (ML) with the spatio‐temporal evolution of biofluid droplets to reveal how drying and self‐assembly encode distinctive compositional fingerprints. By leveraging textural features and interpretable ML, it achieves robust classification of blood abnormalities with over 95% accuracy.
Anusuya Pal, Amalesh Gope, Miho Yanagisawa   +2 more
wiley   +1 more source

Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial

American Journal of Hematology, EarlyView.
ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth, Wilma Barcellini, Christine Ademokun, Junho Jang, Maria Luisa Lozano, David Valcarcel Ferreiras, Cristina Pascual‐Izquierdo, Shripad Chitnis, Sofiya Matviykiv, Alessandra Vitaliti, Chi Chen, Vasiliki Katsanou, Raghav Chawla, Hanny Al‐Samkari   +13 more
wiley   +1 more source

Targeted Medical Therapies for Vascular Anomalies: A Clinical Review

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Vascular anomalies represent a broad spectrum of disorders characterized by aberrant blood or lymphatic vessel development, which can lead to complex clinical phenotypes. Historically, vascular anomalies were classified solely on the basis of their clinical and histopathologic features.
Whitney Eng
wiley   +1 more source

STUDY OF SOCIO-DEMOGRAPHIC CHARACTERISTICS OF PATIENTS WITH CONGENITAL COAGULATION DISORDERS

, 2009
Enas Talib Abdul-Karim, Saad Fadhil Mohammed   +1 more
openalex   +1 more source

Factor Analysis‐Based Quantitative Endotyping Improves Associations With CRS Cross‐Sectional and Longitudinal Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disease characterized by persistent sinonasal inflammation. There is increasing interest in endotype‐based classification, which categorizes CRS based on underlying inflammatory pathways.
Brooke N. Gleason, Zhidi Luo, Aditi Agarwal, Siyuan Dong, Regan L. Harmon, Junqin Bai, Chun‐Kang Liao, Julia Huang, David B. Conley, Kevin C. Welch, Robert C. Kern, Stephanie S. Smith, Anju T. Peters, Whitney S. Stevens, Atsushi Kato, Lutfiyya N. Muhammad, Bruce K. Tan   +16 more
wiley   +1 more source

Daclatasvir and Asunaprevir Combination Therapy-induced Hepatitis and Cholecystitis with Coagulation Disorder due to Hypersensitivity Reactions. [PDF]

Intern Med, 2016
Miyashima Y, Honma Y, Miyagawa K, Oe S, Senju M, Shibata M, Hiura M, Abe S, Harada M.   +8 more
europepmc   +1 more source

Collaboration between clinicians and laboratory diagnosticians can improve outcomes for patients with coagulation disorders [PDF]

Megan McKown, Marjory B. Brooks, Robert Goggs   +2 more
openalex   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Role of leukocytes in hemostasis during orthotopic liver transplantation [PDF]

, 1993
Bechstein, W. O., Himmelreich, G., Huhn, D., Jochum, Marianne, Machleidt, W., Muser, M., Neuhaus, P., Riess, H., Roissaint, R.   +8 more
core   +1 more source

Coagulation factor XII in thrombosis and inflammation.

Blood, 2018
C. Maas, T. Renné
semanticscholar   +1 more source