Results 61 to 70 of about 363,375 (369)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Lupus Antibody Mimicking Reduced Plasmatic Coagulation in a Patient With Atrial Fibrillation and Ischemic Stroke

Frontiers in Neurology, 2020
Background: Lupus anticoagulant (LA) owns procoagulant properties in vivo and prolongs phospholipid-dependent clotting times in vitro. The prolonged in vitro clotting time can be misinterpreted as a bleeding disorder.
Aydin Huseynov, Aydin Huseynov, Verena Haselmann, Maximillian Kittel, Thomas Bertsch, Angelika Alonso, Michael Neumaier, Martin Borggrefe, Martin Borggrefe, Ursula Hoffmann, Ursula Hoffmann   +10 more
doaj   +1 more source

Evaluation of coagulation parameters in dogs with gallbladder mucoceles

Journal of Veterinary Internal Medicine, 2021
Background Gallbladder mucocele (GBM) is a common biliary disorder in dogs. Limited information is available on the coagulation status of dogs with GBM. Hypothesis/Objectives To determine patterns of coagulation alterations in dogs with GBM and correlate
Michelle Pavlick, Armelle DeLaforcade, Dominique G. Penninck, Cynthia R. L. Webster   +3 more
doaj   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Real-time electrical impedimetric monitoring of blood coagulation process under temperature and hematocrit variations conducted in a microfluidic chip.

PLoS ONE, 2013
Blood coagulation is an extremely complicated and dynamic physiological process. Monitoring of blood coagulation is essential to predict the risk of hemorrhage and thrombosis during cardiac surgical procedures.
Kin Fong Lei, Kuan-Hao Chen, Po-Hsiang Tsui, Ngan-Ming Tsang   +3 more
doaj   +1 more source

Coagulation Dysfunction in Acute Respiratory Distress Syndrome and Its Potential Impact in Inflammatory Subphenotypes

Frontiers in Medicine, 2021
The Acute Respiratory Distress Syndrome (ARDS) has caused innumerable deaths worldwide since its initial description over five decades ago. Population-based estimates of ARDS vary from 1 to 86 cases per 100,000, with the highest rates reported in ...
Samantha A. Livingstone, Samantha A. Livingstone, Karin S. Wildi, Karin S. Wildi, Karin S. Wildi, Heidi J. Dalton, Asad Usman, Katrina K. Ki, Katrina K. Ki, Margaret R. Passmore, Margaret R. Passmore, Gianluigi Li Bassi, Gianluigi Li Bassi, Gianluigi Li Bassi, Jacky Y. Suen, Jacky Y. Suen, John F. Fraser, John F. Fraser   +17 more
doaj   +1 more source

Automation of the Continuous Coagulation Monitor [PDF]

, 1974
The development of automation in the past 50 years has paralleled the accelerating growth of today’s vast technological society. Automatic control systems are indispensable extensions of man\u27s brain that enable him to monitor and regulate his complex ...
Mitchell, Dee, Oskowis, James J.
core   +2 more sources

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Coagulation tests or standardized questionnaire, which is better as a predictor of bleeding? A prospective study among children before tonsillectomy and/or adenoidectomy

BMC Research Notes, 2020
Objective The value of pre-operative coagulation testing for adenotonsillar surgery is controversial. The purpose of this study was to evaluate the role of routine coagulation tests and a standardized questionnaire in children before tonsillectomy and/or
Muhamed Masalha, Ari DeRowe, Salim Mazzawi, Tzvi Chen, Rami Ghanayim, Roee Landsberg, Ariel Koren   +6 more
doaj   +1 more source

Haematalogical investigations in children [PDF]

, 2009
The haematology laboratory is able to perform a number of tests to help establish the cause of illness in children. The full blood count (FBC, also known as a complete blood count, CBC) is one of the most basic blood tests performed on children ...
Chalmers, E.A., Halsey, C.
core