Results 221 to 230 of about 32,663 (321)

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi   +18 more
wiley   +1 more source

Sex Differences in Outcomes of Adults with Repaired Coarctation of Aorta and Concomitant Aortic Valve Disease. [PDF]

open access: yesCJC Open
Egbe AC   +6 more
europepmc   +1 more source

Persistent Hypertension and Left Ventricular Hypertrophy After Repair of Native Coarctation of Aorta in Adults. [PDF]

open access: yesHypertension, 2021
Egbe AC   +6 more
europepmc   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

open access: yesAdvanced Science, Volume 12, Issue 47, December 18, 2025.
Abstract Aging is a complex, multifaceted process affecting all organ systems, with vascular aging playing a central role in organismal health decline. Beyond its role in circulation, the vascular system acts as a dynamic interface between tissues, influencing countless physiological functions such as tissue regeneration and repair, immune responses ...
Mattia Cenciarini   +4 more
wiley   +1 more source

Incidence, Correlates, and Prognostic Implications of New-Onset Atrial Fibrillation in Adults With Repaired Coarctation of Aorta. [PDF]

open access: yesCJC Pediatr Congenit Heart Dis
Egbe AC   +5 more
europepmc   +1 more source

Coarctation of the Aorta and Interrupted Aortic Arch

open access: hybrid, 2006
Laura A. Hastings, David G. Nichols
openalex   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang   +19 more
wiley   +1 more source

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