Results 251 to 260 of about 32,663 (321)

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials

open access: yesESC Heart Failure, Volume 12, Issue 6, Page 3878-3898, December 2025.
This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz   +5 more
wiley   +1 more source

Pathogenic glycosyltransferase genes and potential therapeutic drugs in pressure overload‐induced heart failure

open access: yesESC Heart Failure, Volume 12, Issue 6, Page 4108-4124, December 2025.
Abstract Aims Protein glycosylation regulated by glycosyltransferases is an important type of post‐translational modification. The role of the glycosyltransferase genes (GTGs) in heart failure (HF) remains unclear and requires further investigation.
Jiahe Wu   +5 more
wiley   +1 more source

Coarctation of aorta intervention: When covered stents should have been first choice?

open access: yesAnn Pediatr Cardiol, 2021
Rajan P   +4 more
europepmc   +1 more source

Double Aortic Arch with Coarctation of Aorta in an Adolescent: Unraveling the Vascular Ring. [PDF]

open access: yesAorta (Stamford), 2020
Rajbanshi BG   +8 more
europepmc   +1 more source

Re‐PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

open access: yesESC Heart Failure, Volume 12, Issue 6, Page 4495-4502, December 2025.
Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal   +9 more
wiley   +1 more source

Contrast-enhanced MR angiography of thoracic vascular malformations in a pediatric population. [PDF]

open access: yes, 2003
Caseiro-Alves, F   +3 more
core   +1 more source

Impact of epicardial adipose tissue on myocardial function and structure in patients with severe aortic valve stenosis

open access: yesESC Heart Failure, Volume 12, Issue 6, Page 4230-4241, December 2025.
Epicardial adipose tissue (EAT) has been linked to adverse remodelling and outcomes in aortic valve stenosis (AS), yet mechanisms remain unclear. In 137 patients with severe AS undergoing CMR before TAVR, higher EAT (≥46.5 ml/m2) was associated with impaired left atrial (LA) reservoir strain, while ventricular morphology, function and tissue ...
Judith Gronwald   +10 more
wiley   +1 more source

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