Results 131 to 140 of about 19,292 (290)

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai   +7 more
wiley   +1 more source

Does the degree of coarctation of the aorta influence wall shear stress focal heterogeneity?

open access: yesAnnual International Conference of the IEEE Engineering in Medicine and Biology Society, 2016
John P. Gounley   +8 more
semanticscholar   +1 more source

Prolonged postnatal adaptation and enhanced prevalence of congenital heart diseases due to altitude may contribute to newborn mortality in Bolivia

open access: yesExperimental Physiology, EarlyView.
Abstract Highland populations suffer from significant infant mortality due to chronic ambient hypoxia, which increases the risk of congenital heart disease (CHD) and neonatal pulmonary hypertension. Neither the prevalence of these conditions nor the effectiveness of neonatal cardiac screening to identify CHD or pulmonary hypertension among neonates ...
Alexandra Heath   +12 more
wiley   +1 more source

The multifaceted roles of ketones in physiology

open access: yesExperimental Physiology, EarlyView.
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili   +3 more
wiley   +1 more source

Integrative cardiovascular dose–response to graded lower‐body negative pressure

open access: yesExperimental Physiology, EarlyView.
ABSTRACT Lower‐body negative pressure (LBNP) has been posited as a potential spaceflight countermeasure to counteract the physiological deconditioning related to fluid shifts in microgravity. However, open questions remain regarding the magnitude of LBNP that should be applied.
Richard S. Whittle   +5 more
wiley   +1 more source

Microelectrode recordings from the human cervical vagus nerve during maximal breath‐holds

open access: yesExperimental Physiology, EarlyView.
Abstract Voluntary breath‐holds can be sustained for a long time following training, but ultimately, regardless of duration, the asphyxic break‐point is reached and the apnoea terminated. The physiological changes occurring during the apnoea include a marked increase in sympathetically‐mediated vasoconstriction in non‐essential organs, such as skeletal
Vaughan G. Macefield   +7 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker   +2 more
wiley   +1 more source

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