Results 171 to 180 of about 26,925 (267)

Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A

Phytotherapy Research, Volume 40, Issue 5, Page 2710-2729, May 2026.
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen, Xinghong Zhou, Yanting You, Jieyu Chen, Baizhao Peng, Yijian Deng, Shuai Ji, Ying Yang, Xiaohu Chen, Huaxi Liu, Shuxuan Yang, Hiu Yee Kwan, Wen Jin, Lei Zhang, Yuegang Wang, Xiaoshan Zhao, Yanyan Liu   +16 more
wiley   +1 more source

Influence of atrial septal defect on mitral valve growth after repair of coarctation of the aorta or an interrupted aortic arch in infants. [PDF]

Clin Exp Pediatr
Wang YC, Chou HW, Huang CH, Huang HH, Chen YS, Wu ET, Chen SJ, Lin MT, Chiu SN, Huang SC.   +9 more
europepmc   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, Volume 40, Issue 5, Page 2878-2894, May 2026.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source

Multidirectional flow analysis by cardiovascular magnetic resonance in aneurysm development following repair of aortic coarctation [PDF]

, 2008
Alex Frydrychowicz, Raoul Arnold, Daniel Hirtler, Christian Schlensak, Aurelien F Stalder, Jürgen Hennig, Mathias Langer, Michael Markl   +7 more
core   +1 more source

A case of blurred vision due to coarctation of the aorta, an early clinical presentation, or just a coincidence? [PDF]

Medicine (Baltimore)
Xiao Z, Fu J, Li C, Gong J, Zhang Y.
europepmc   +1 more source

Postoperative chylothorax following surgical transection of a left ligamentum arteriosum in a cat with a persistent right aortic arch

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 6‐month‐old intact female domestic shorthair cat was presented for surgical correction of a vascular ring anomaly. The main clinical sign on presentation was persistent regurgitation after ingestion of solid food. Computed tomography of the thorax confirmed the diagnosis of a persistent right aortic arch (PRAA) with a left ligamentum ...
Adriaan D. Pont, Elizabeth G. Bester, Adriaan M. Kitshoff   +2 more
wiley   +1 more source

Vascular remodeling in adults after coarctation repair: impact of descending aorta stenosis and age at surgery [PDF]

, 2010
Olga Trojnarska, Ludwina Szczepaniak-Chicheł, Katarzyna Mizia-Stec, Marcin Gabriel, Agnieszka Bartczak, Stefan Grajek, Zbigniew Gąsior, Lucyna Kramer, Andrzej Tykarski   +8 more
core   +1 more source

Renal Doppler as a Diagnostic Clue to Post-ductal Coarctation of the Aorta in an Adolescent Male: A Case Report. [PDF]

Cureus
Srivastava M, Seth N.
europepmc   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, Volume 183, Issue 9, Page 1939-1957, May 2026.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Delayed Diagnosis of Coarctation of the Aorta in a Hypertensive Child: Challenges in Early Detection. [PDF]

Cureus
Hisatomi R, Mahajan S, Liu R.
europepmc   +1 more source