Results 251 to 260 of about 2,738,317 (296)

Repaired coarctation of the aorta does not affect four-dimensional flow metrics in bicuspid aortic valve disease. [PDF]

Interdiscip Cardiovasc Thorac Surg
Kiljander T, Kauhanen P, Sillanmäki S, Lottonen-Raikaslehto L, Husso M, Ylä-Herttuala E, Saari P, Kokkonen J, Laukkanen J, Mustonen P, Hedman M.   +10 more
europepmc   +1 more source

The isolated, perfused working heart preparation of the mouse—Advantages and pitfalls

Acta Physiologica, Volume 241, Issue 4, April 2025.
Abstract Isolated, perfused hearts are viable for hours outside the body, and important research findings have been made using mouse hearts ex vivo. In the Langendorff perfusion mode, the coronary tree is perfused via retrograde flow of a perfusate down the ascending aorta.
Diana S. Usai, Ellen Aasum, Morten B. Thomsen   +2 more
wiley   +1 more source

Novel Technique to Percutaneous Stent Implantation for Coarctation of the Aorta: Safari Wire Pacing. [PDF]

Anatol J Cardiol
Barış VÖ, Poyraz F, Kaya EE.
europepmc   +1 more source

Hypoxia and ischemic stroke modify cerebrovascular tone by upregulating endothelial BK(Ca) channels—Lessons from rat, pig, mouse, and human

Acta Physiologica, Volume 241, Issue 4, April 2025.
Abstract Aim In animal models and human cerebral arteries, the changes in endothelial cell (EC)‐large conductance calcium‐activated potassium channel (BKCa) distribution, expression, and function were determined in hypoxia and ischemic stroke. The hypothesis that hypoxia and ischemic stroke induce EC‐BKCa in cerebral arteries was examined.
Christian Staehr, Victoria Hinkley, Vladimir V. Matchkov, Rajkumar Rajanathan, Line Mathilde B. Hansen, Yvonne Eiby, Nathan Luque, Ian Wright, Stella T. Bjorkman, Stephanie M. Miller, Rohan S. Grimley, Andrew Dettrick, Kirat Chand, Hong L. Nguyen, Nicole M. Jones, Tim V. Murphy, Shaun L. Sandow   +16 more
wiley   +1 more source

Sudden death in adults with repaired coarctation of the aorta: A case for sex-based risk factors. [PDF]

Int J Cardiol Congenit Heart Dis
Lastinger L, Lee M, Hassen L, Cavus O, Rajpal S, Moore JP, Mah ML, Bradley EA.   +7 more
europepmc   +1 more source

Pharmacological profiling of small molecule modulators of the TMEM16A channel and their implications for the control of artery and capillary function

British Journal of Pharmacology, Volume 182, Issue 8, Page 1719-1740, April 2025.
Abstract Background and purpose TMEM16A chloride channels constitute a depolarising mechanism in arterial smooth muscle cells (SMCs) and contractile cerebral pericytes. TMEM16A pharmacology is incompletely defined. We elucidated the mode of action and selectivity of a recently identified positive allosteric modulator of TMEM16A (PAM_16A) and of a range
Rumaitha Al‐Hosni, Emilio Agostinelli, Zeki Ilkan, Lara Scofano, Rachel Kaye, Ria L. Dinsdale, Kathryn Acheson, Andrew MacDonald, Dean Rivers, Alice Biosa, Martin J. Gunthorpe, Frances Platt, Paolo Tammaro   +12 more
wiley   +1 more source

4D pathology: translating dynamic epithelial tubulogenesis to prostate cancer pathology

Histopathology, Volume 86, Issue 5, Page 681-693, April 2025.
Rethinking prostate cancer growth patterns in the context of epithelial tubule formation, elongation, and branching. The Gleason score is the gold standard for grading of prostate cancer (PCa) and is assessed by assigning specific grades to different microscopical growth patterns.
Hridya Harikumar, Martin E van Royen, Geert JLH van Leenders   +2 more
wiley   +1 more source

The role of atherosclerosis in HIV‐associated vasculopathy in young South African stroke patients

HIV Medicine, Volume 26, Issue 4, Page 633-642, April 2025.
Abstract Background HIV‐associated vasculopathy is known to cause stroke in people living with HIV (PLWH). The role of atherosclerosis is unclear. We assessed the aetiology of vasculopathy in PLWH and tested the utility of markers of subclinical atherosclerosis to distinguish atherosclerotic (AV) from non‐atherosclerotic vasculopathy (NAV).
Eitzaz Sadiq, Angela Woodiwiss, Grace Tade, Jeremy Nel, Gavin Norton, Girish Modi   +5 more
wiley   +1 more source