Results 51 to 60 of about 2,738,317 (296)

P21‐Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy

open access: yesAdvanced Science, EarlyView.
Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li   +21 more
wiley   +1 more source

Abdominal aorta coarctation: The first three case reports in our literature [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2010
Introduction. Congenital coarctation of the thoracic aorta at the ligamentum arteriosum or the aortic arch is well recognized. But a much less common variety (0.5-2.0%) of aortic coarctation is located in the distal thoracic aorta or abdominal aorta or ...
Gajin Predrag   +4 more
doaj   +1 more source

Beat Pressure and Comparing it with Ascending Aorta Pressure in Normal and Abnormal Conditions [PDF]

open access: yes4th European Conference of the International Federation for Medical and Biological Engineering, pp. 276-285. Springer Berlin Heidelberg, 2009, 2014
Lumped method (Electrical analogy) is a quick and easy way to model human cardiovascular system. In this paper Lumped method is used for simulating a complete model. It describes a 36-vessel model and cardiac system of human body with details that could show hydrodynamic parameters of cardiovascular system.
arxiv   +1 more source

Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia‐Induced Vascular Injury

open access: yesAdvanced Science, EarlyView.
Mitophagy switching drives high‐glucose‐induced vascular endothelial injury. Short‐term high‐glucose exposure upregulates Fis1 expression and enhances Fis1‐TBC1D15 interaction, activating Parkin‐mediated mitophagy. Long‐term high‐glucose exposure reduces Fis1 expression, inhibiting Parkin‐mediated mitophagy and triggering mitophagy switching from ...
Anqi Luo   +10 more
wiley   +1 more source

Coarctation of Aorta Masquerading as a Spinal Arteriovenous Malformation: A Case Report

open access: yesEuropean Medical Journal Cardiology
Coarctation of the aorta is a congenital disease involving the cardiovascular system. It has a varied presentation and is often under-diagnosed in clinical practice. The authors report a case of an unusual presentation of coarctation of the aorta with a
Padma Vikram Badhe   +3 more
doaj   +1 more source

Long-term outcomes of surgical repair of isolated coarctation of the aorta in different age groups

open access: yesBMC Surgery, 2023
Background Coarctation of the aorta (CoA) is one of the most common congenital heart defects (5–8% of all CHD). Treatment of native CoA may be accomplished surgically, or through an interventional approach.
Alwaleed Al-Dairy
doaj   +1 more source

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

open access: yesAdvanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Descending thoracic aorta–abdominal aortic bypass and bilateral renal arterial blood circulation reconstruction are effective in atypical coarctation of the aorta with heart failure: a case report

open access: yesJournal of Cardiothoracic Surgery, 2021
Background There are a lot of reports of the renal failure and heart failure due to coarctation of the aorta. However, there are no case reports in which revascularization dramatically improved left ventricular function in patients with progressive ...
Takuma Mikami   +12 more
doaj   +1 more source

Using the Polar Transform for Efficient Deep Learning-Based Aorta Segmentation in CTA Images [PDF]

open access: yesarXiv, 2022
Medical image segmentation often requires segmenting multiple elliptical objects on a single image. This includes, among other tasks, segmenting vessels such as the aorta in axial CTA slices. In this paper, we present a general approach to improving the semantic segmentation performance of neural networks in these tasks and validate our approach on the
arxiv  

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

open access: yesAdvanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong   +15 more
wiley   +1 more source

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