Results 91 to 100 of about 40,345 (254)

Coats' disease and calcification: a case report.

open access: yes, 1996
Intraocular calcification can rarely occur in Coats' disease. To our best knowledge, all previously reported cases with intraocular calcification had significant exudative detachment.
Memisoglu, B.   +4 more
core  

Bilateral Fluorescein Angiographic Findings in Unilateral Coats’ Disease

open access: yes, 2011
Two patients with clinically unilateral Coats' disease were imaged with fluorescein angiography during an examination under anesthesia. Both patients were found to have abnormal retinal vasculature in their contralateral eye. These findings may represent
Ditte J. Hess   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Modified transscleral external drainage of subretinal fluid in high bullous exudative retinal detachment due to Coats' disease

open access: yesOman Journal of Ophthalmology, 2018
Surgical management of advanced coats' disease has always been a challenge to a surgeon. Various different techniques have been tried. With the advancement in surgical instruments and machines, surgeons are now modifying older surgical techniques.
Shachi Rohan Desai   +3 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Coats disease in Saudi Arabia

open access: yes, 2019
Purpose: : to study the features and treatment outcomes of Coats disease in Saudi Arabia Methods: : retrospective chart review of patients with Coats disease registered at the King Khaled Eye Specialist Hospital from 1983-2010 Results: : Twenty out
Alqahtani, Abdullah A., Ghazi, Nicola G.
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Coats' disease and Fuchs' heterochromic cyclitis

open access: yes, 1994
The authors present an interesting case of a young boy with unilateral Coats' disease who after ten years of follow-up developed Fuchs' heterochromic cyclitis in the same ...
Kritzinger, E E   +2 more
core   +1 more source

Bilateral Coats’ Disease Combined with Retinopathy of Prematurity [PDF]

open access: yes, 2015
Purpose. To report a case of bilateral Coats’ disease combined with retinopathy of prematurity (ROP). Case. Retinal vascularization was complete in the right eye, whereas zone III, stage 3 ROP and preplus disease were observed in the left eye at 43 weeks
Huseyin Aslan   +5 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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