Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian +11 more
wiley +1 more source
Couple-close: Unified approach to semisaturated cyclic scaffolds. [PDF]
Xie J +9 more
europepmc +1 more source
Magneto‐X Effects in Magnetic Soft Materials and Their Applications
This review systematically explores magnetic soft materials (MSMs), a novel class of composites that transform under magnetic fields. It catalogs fundamental “Magneto‐X” effects, classifies materials by their matrix and magnetic fillers, and highlights transformative applications in soft robotics, biomedical devices, flexible electronics, etc. Finally,
Ziyin Xiang +5 more
wiley +1 more source
Synthesis, structural characterization, DFT calculation, and antitumor activity of a new Co(II) complex based on 2-((2'-Carboxybenzyl)oxy)benzoic acid and 2,2'-bipyridine ligands. [PDF]
Sui BL +5 more
europepmc +1 more source
Redefining the Health Risk of Battery Materials Through a Biologically Transformed Metal Mixture
Inhaled NCM particles undergo lysosomal degradation, releasing complex ion mixtures that induce systemic impact. The impact is determined by a critical balance between antagonistic Ni‐Co interactions and synergistic Mn effects. To capture these complexities in risk assessment, we develop an IAI model, ensuring a more accurate quantitative risk ...
Ze Zhang +11 more
wiley +1 more source
Temporal rich-club phenomenon and its formation mechanisms in international trade: Evidence from new energy minerals. [PDF]
Tang Q +5 more
europepmc +1 more source
A lithium‐bearing slag is investigated with the goal of holistic valorization. The present β‐eucryptite (LiAlSiO4) exhibits a high lithium content and low levels of impurities. The spinel contains most of the chromium and vanadium, representing additional valorization opportunities.
Peter Cornelius Gantz +9 more
wiley +1 more source
Facile synthesis of Co-based catalysts with high dispersion <i>via</i> an eco-friendly strategy. [PDF]
Gu F +5 more
europepmc +1 more source
High‐throughput screening led to the identification of 67 Z‐scheme heterojunctions (comprising 2D magnetic transition metal halides and non‐magnetic transition metal chalcogenides). For CrI3/MoTe2 and CrI3/WTe2, electronic structure analysis demonstrated that synergistic crystallographic point group and built‐in electric field effects generate a ...
Hongyang Ren +8 more
wiley +1 more source
Transfer accuracy of three different virtually designed CAD/CAM retainers - baseline results of a randomized clinical trial. [PDF]
Linnerz F +7 more
europepmc +1 more source

