Results 41 to 50 of about 13,397 (223)

Sensitivity studies of CdZnTe semiconductor detectors for the COBRA experiment [PDF]

open access: yes, 2012
The COBRA Experiment searches for Neutrinoless Double Beta Decay. The observation of this decay would provide the absolute mass of the neutrino and clarify the question whether the neutrino is its own anti particle, a so called Majorana particle, or not.
Köttig, Tobias
core   +1 more source

Entwurf und Implementierung eines generischen CoBRA-Werkzeugs

open access: yes, 2022
This project thesis deals with the development of software tool to support the CoBRA method. CoBRA is a Cost Estimation, Benchmarking and Risk Analysis method for software projects developed by Fraunhofer IESE.
Kläs, M.
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

COBRA-Seq: Sensitive and Quantitative Methylome Profiling

open access: yes, 2015
Combined Bisulfite Restriction Analysis (COBRA) quantifies DNA methylation at a specific locus. It does so via digestion of PCR amplicons produced from bisulfite-treated DNA, using a restriction enzyme that contains a cytosine within its recognition ...
Jason Ross   +4 more
core   +1 more source

Adaption of COBRA Method for The Investigation of Nutrition-Based DNA Methylation Mechanism in Escherichia coli

open access: yesIğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2020
Epigenetics are changes that occur in the DNA sequence due to environmental conditions. In last few decades epigenetics has been one of the most important advances in biology and related fields. It is very important in that it offers a new approach to all relevant disciplines, especially biology, to explain how DNA sequencing in an epigenetic organism ...
Taha Yasin KOÇ   +3 more
openaire   +5 more sources

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

open access: yesAdvanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza   +9 more
wiley   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon   +20 more
wiley   +1 more source

COBRA: A Combined Regression Strategy

open access: yes, 2016
International audienceA new method for combining several initial estimators of the regression function is introduced. Instead of building a linear or convex optimized combination over a collection of basic estimators $r_1,\dots,r_M$, we use them as a ...
Biau, Gérard   +3 more
core   +1 more source

Safety and Feasibility of Novel Reconstruction Method Using Long and Narrow Cobra- Head- Shaped Gastric Tube in Laparoscopic Proximal Gastrectomy for Cancer [PDF]

open access: yes, 2021
Abstract Background. To clarify the safety and feasibility of laparoscopic proximal gastrectomy (LPG) with our novel reconstruction methods, clinical outcomes of this LPG were evaluated and compared to those of LPG with our conventional method. Methods.
Yoshitake Ueda   +8 more
openaire   +1 more source

Evaluation of Financial and Operational Sustainability with Multi-Criteria Decision-Making Methods: An Application in the US Airline Market

open access: yesStudies in Business and Economics
The aim of this study is to investigate the multi-dimensional effects of the Covid-19 pandemic on the sustainability performance of airlines in the U.S.
Asker Veysi
doaj   +1 more source

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