Results 41 to 50 of about 12,395 (181)

Supervised Machine Learning Approach to Iron Meteorite Classification Using Random Forest: A Predictive Model to Classify Ungrouped Irons

open access: yesEarth and Space Science, Volume 13, Issue 8, August 2026.
Abstract Iron meteorites provide insight into the formation processes of planetary cores from the early Solar System. Through further classifying individual irons into specific groups, which are assumed to represent a common parent body, greater information can be yielded into the formation processes of those bodies.
A. F. Rogers   +4 more
wiley   +1 more source

Integrating Artificial Intelligence Into Drug Discovery From Medicinal Plants: Current Applications and Infrastructural Challenges

open access: yesChemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
This review presents a systems‐oriented roadmap for integrating artificial intelligence into medicinal plant drug discovery to overcome persistent bottlenecks like extract complexity. It highlights that advancing toward reproducible therapeutics requires making phytochemical datasets AI‐ready via rigorous harmonization and phyto‐centric foundational ...
Amit Gangwal   +5 more
wiley   +1 more source

Efecto de la concentración de poliacrilamida sobre la calidad del depósito de cobre obtenido por refino electrolítico

open access: yesRevista de Metalurgia, 2013
El efecto del aditivo poliacrilamida no iónica (PAM), se estudió a nivel de laboratorio, como afinador de grano cristalino en el refino electrolítico del cobre.
J. Aragón   +4 more
doaj   +1 more source

Formative evaluation results of a phase 2 Center of Biomedical Research Excellence (COBRE)

open access: yesJournal of Clinical and Translational Science, 2020
Introduction: Because a primary focus of Centers of Biomedical Research Excellence (COBRE) is the development of junior-level investigators into competent and successful research scientists, evaluation of their skills, mentoring experiences, and ...
Judy A. Kimberly   +3 more
doaj   +1 more source

A Non‐Canonical Role for Hepatocyte MLKL in Promoting Mitochondrial Dysfunction and Senescence in the Aging Liver

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
Aging‐associated MLKL upregulation in hepatocytes induces mitochondrial dysfunction and oxidative stress, accompanied by increased release of pro‐inflammatory extracellular vesicles. These changes are associated with increased p16+/p21+ senescence in hepatocytes and non‐parenchymal cells (macrophages, stellate cells, and endothelial cells), suggesting ...
Sabira Mohammed   +21 more
wiley   +1 more source

Amenizante Orgânico e Eucalyptus grandis para Fitoestabilização de Solo Contaminado com Cobre

open access: yesFloresta e Ambiente, 2017
RESUMO Este trabalho avaliou a utilização de turfa como amenizante e Eucalyptus grandis como técnica de fitoestabilização para remediar solo contaminado com cobre. O trabalho foi conduzido sob delineamento inteiramente casualizado em arranjo fatorial (2 ×
Rudinei De Marco   +4 more
doaj   +1 more source

Naturally Occurring CodY Variants Alter Ligand Binding, DNA Target Affinity, and Virulence in Clostridioides difficile

open access: yesMolecular Microbiology, Volume 126, Issue 1, Page 98-110, July 2026.
Single amino acid substitutions in the global regulator CodY can alter nutrient sensing and virulence regulation in Clostridioides difficile. We show that the CodY(Y146N) and CodY(V58A) variants display altered ligand binding and reduced promoter binding, leading to derepression of toxin regulatory pathways and increased virulence in vivo.
Md Kamrul Hasan   +2 more
wiley   +1 more source

Postbiotic Stool Filtrates From Patients With Type 2 Diabetes Impair Mouse Intestinal Muscle Contractility Ex Vivo and Alter Enteric Cholinergic Neuronal Activity in Vivo

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 7, July 2026.
We previously showed that molecules solubilized in filter‐sterilized stool filtrates (postbiotic stool filtrates; PSFs) of mice fed a high‐fat diet (HFD) may have a role in triggering damage to the enteric nervous system and gut dysmotility before the onset of T2D symptoms. To translate these results, we studied the effects of PSFs from male and female
Peter F. Voller   +14 more
wiley   +1 more source

The role of Research‐Practice Ambassadors in strengthening socially just and equitable partnership processes

open access: yesAmerican Journal of Community Psychology, Volume 77, Issue 3-4, Page 527-538, June 2026.
Abstract Research‐Practice Partnerships seek to close the research‐practice gap through developing collaborative, authentic partnerships between researchers and community members. Our team has leveraged Research‐Practice Ambassadors to support socially just and equitable partnership processes in schools.
Danielle R. Hatchimonji   +8 more
wiley   +1 more source

Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Sleep disruption is an early feature of Alzheimer's disease (AD), but the cellular mechanisms linking amyloid pathology to sleep loss remain unclear. METHODS Electroencephalography/electromyography (EEG/EMG) recordings, quantitative EEG analysis, and sleep deprivation were performed in APPswe/PSEN1dE9 (APP/PS1) mice at different ...
Nicholas J. Constantino   +9 more
wiley   +1 more source

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