Results 181 to 190 of about 47,347 (285)
Evolutionary constraints impose multiple checkpoints that block mammalian sensory hair cell regeneration. [PDF]
Zhang X, Su Z, Guan D, Liu X, Xie H.
europepmc +1 more source
Cilia in Nervous System Development, Function, and Disease
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley +1 more source
Transcriptomic characters of cochlear vascular cells with pericyte-driven angiogenetic activity. [PDF]
Wang P +5 more
europepmc +1 more source
MYO6 and Heart: A Novel Variant in a Deaf Infant With Supraventricular Tachycardia
A novel homozygous frameshift variant in the MYO6 gene (c.2496_2497delAC; p.H833Qfs*5) was identified in a neonate presenting with bilateral congenital sensorineural hearing loss, paroxysmal supraventricular tachycardia (SVT), and prolonged QT interval.
Samira Kalayinia +5 more
wiley +1 more source
Live imaging and multimodal profiling reveal transdifferentiation of a cochlear supporting cell subpopulation upon Notch inhibition. [PDF]
Khalaily L +9 more
europepmc +1 more source
Abstract MYO7A is a causal gene, underlying Usher syndrome type 1B (USH1B) and both autosomal recessive (DFNB2) and dominant (DFNA11) non‐syndromic hearing loss. Despite the large number of reported MYO7A variants (over 2,200), variants located in an extended splice region remain difficult to interpret and are often classified as variants of uncertain ...
Tao Shi +5 more
wiley +1 more source
Deep learning for discriminating cochlear malformations on temporal bone CT. [PDF]
Li Z +5 more
europepmc +1 more source
ABSTRACT Background Accurate setting of maximum comfort levels (MCL) during cochlear implant (CI) fitting is essential but subjective, especially in non‐cooperative patients. The stapedius reflex (SR) correlates with the MCL and offers an objective measure.
Dirk Arnold +4 more
wiley +1 more source
Conditional knockout of Dkk3 drives Lgr5+ progenitor reprogramming into hair cells in the mouse cochlea. [PDF]
Xiao H +14 more
europepmc +1 more source

