Results 271 to 280 of about 66,419 (330)

Diffusion Schrödinger bridge models for high‐quality MR‐to‐CT synthesis for proton treatment planning

open access: yesMedical Physics, Volume 52, Issue 7, July 2025.
Abstract Background In recent advancements in proton therapy, magnetic resonance (MR)‐based treatment planning is gaining momentum due to its excellent soft tissue contrast and high potential to minimize extra radiation exposure compared to traditional computed tomography (CT)‐based methods. This transition underscores the critical need for accurate MR‐
Muheng Li   +4 more
wiley   +1 more source

Long‐Term Outcomes and Quality of Life of Children With Intracranial Ependymoma Treated With Pencil Beam Scanning Proton Therapy

open access: yesPediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Background Ependymoma is a common brain tumor in children and adolescents. Adjuvant radiation therapy improves prognosis but carries potential toxicity risks, particularly for young patients. Proton therapy (PT) offers better conformal treatments and reduces dose exposure compared to traditional photon radiotherapy.
Eymeric Le Reun   +6 more
wiley   +1 more source

Quantitative Proteomics of Cochlear Tissues: Bilateral Comparisons in Guinea Pigs and Rats

open access: yesPROTEOMICS, Volume 25, Issue 13, July 2025.
ABSTRACT The cochlea, an incredibly sensitive sensory system, detects sound waves and converts them into electrical signals the brain recognizes as sound. Damage to cochlear hair cells can release proteins, triggering biological responses that may impair hearing.
Motahare Khorrami   +3 more
wiley   +1 more source

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 14, Page 3109-3134, July 2025.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf   +10 more
wiley   +1 more source

The Neural Reality of Pitch Chroma in Early Infancy

open access: yesDevelopmental Science, Volume 28, Issue 4, July 2025.
ABSTRACT At the physical level, the experience of pitch has a single determinant: the repetition rate of a waveform in the acoustic signal. Yet, psychologists describe pitch as composed of two perceptual dimensions, height and chroma. Chroma accounts for octave equivalence, whereby sounds with fundamental frequencies at a 1:2 ratio are perceived as ...
Giulia Gennari   +1 more
wiley   +1 more source

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