Results 201 to 210 of about 71,263 (359)

Machine Learning Feasibility in Cochlear Implant Speech Perception Outcomes-Moving Beyond Single Biomarkers for Cochlear Implant Performance Prediction. [PDF]

open access: yesEar Hear
Shew MA   +12 more
europepmc   +1 more source

Disability, Subject‐Dependence, and the Bad‐Difference View

open access: yesBioethics, EarlyView.
ABSTRACT Philosophers have debated on the “mere‐difference” view of disability, according to which disability as such is neutral in terms of well‐being, just like race and gender. It is contrasted with the “bad‐difference” view, which holds that disability is bad for its possessor even in a non‐ableist situation.
Shu Ishida   +2 more
wiley   +1 more source

The 3D-Robotic Exoscope Compared With the Microscope in Cochlear Implant and Translabyrinthine Surgery. [PDF]

open access: yesLaryngoscope
Crimi N   +7 more
europepmc   +1 more source

Generation and Auditory Phenotypic Characterization of Prps1 p.Ala87Thr Mouse Knock‐In Model for Human DFNX1 Deafness

open access: yesClinical Genetics, EarlyView.
Our mouse model with a c.259G>A transition in PRPS1 showed a significant decrease in the number of hair cells and SGN counts at 48 weeks of age and a reduction in Prps1 enzymatic activity in the KI mouse. This model will serve as a valuable tool for developing therapeutic strategies.
Denise Yan   +6 more
wiley   +1 more source

Implication of GPRASP2 in the Proliferation and Hair Cell‐Forming of Cochlear Supporting Cells

open access: yesCell Proliferation, EarlyView.
Schematic diagram of GPRASP2‐mediated SCs proliferation and HCs formation. GPRASP2 deficiency results in increased lysosomal degradation of SMO. GPRASP2‐mediated SMO/GLI1 signalling promotes SC proliferation, which contributes to HC formation. GPRASP2‐mediated SMO/β‐catenin signalling is implicated in HCs fate specification and differentiation ...
Jing Cai   +9 more
wiley   +1 more source

App-based daily self-measurement of impedance in cochlear implant users. [PDF]

open access: yesFront Neurol
Vormelcher S   +4 more
europepmc   +1 more source

Testing of synthetic vowels in patients with 22 channel cochlear implant.

open access: bronze, 1994
Hiromitsu Saito   +5 more
openalex   +2 more sources

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

open access: yesCell Proliferation, EarlyView.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang   +10 more
wiley   +1 more source

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