Results 281 to 290 of about 71,263 (359)

A novel cochlear implant assessment tool: Audiometric and speech recognition analysis. [PDF]

open access: yesBraz J Otorhinolaryngol
Caldas FF   +6 more
europepmc   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du   +13 more
wiley   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Intact sensorimotor rhythm abilities but altered audiovisual integration in cochlear implant users. [PDF]

open access: yesPLoS One
Valentin O   +6 more
europepmc   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li   +3 more
wiley   +1 more source

Health service use, health outcomes and treatment costs of adults with a cochlear implant: a retrospective cohort study. [PDF]

open access: yesBMC Public Health
Okuba T   +8 more
europepmc   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu   +5 more
wiley   +1 more source

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