Results 291 to 300 of about 72,586 (338)

Comprehensive Genetic Analysis of NF2 in Sporadic Vestibular Schwannoma

open access: yesLaryngoscope Investigative Otolaryngology, Volume 10, Issue 5, October 2025.
Comprehensive genetic analyses, including whole‐exome sequencing, methylation analysis, and MLPA, are essential for accurately identifying NF2 inactivation mechanisms in sporadic vestibular schwannomas. The findings suggest that NF2 methylation may contribute to variations in clinical presentation.
Takeshi Wakabayashi   +14 more
wiley   +1 more source

Optimizing CI Systems for Better Recognition of Soft Speech —the Concept of Broad‐Range Mapping

open access: yesLaryngoscope Investigative Otolaryngology, Volume 10, Issue 5, October 2025.
ABSTRACT Objectives The individual mapping of cochlear implants (CIs) aims to optimize the user's speech understanding. Recent investigations have shown the importance of soft speech: (1) According to Datalog studies, a large proportion of speech components lies in the range below 60 dB, and (2) soft speech represents a separate category in CI outcome,
Matthias Hey, Thomas Hocke
wiley   +1 more source

UFMylation System: Biological Functions, Molecular Mechanisms, Diseases, and Drug Discovery

open access: yesMedComm, Volume 6, Issue 10, October 2025.
UFMylation, a novel ubiquitin‐like modification, plays an essential role in various cellular processes, such as the immune response, DNA damage repair, unfolded protein response (UPR), autophagy, endoplasmic reticulum (ER)‐phagy, stem cell self‐renewal, apoptosis, and metastasis.
Huiyan Li   +5 more
wiley   +1 more source

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