Results 71 to 80 of about 1,083,423 (403)
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang+8 more
wiley +1 more source
Auditory training strategies for adult users of cochlear implants [PDF]
There has been growing interest recently in whether computer-based training can improve speech perception among users of cochlear implants (Fu et al., 2005; Oba et al., 2011; Ingvalson et al., 2013). This paper reports a series of experiments which first
Stacey, PC, Summerfield, AQ
core
Early assessment of vestibular function after unilateral cochlear implant surgery [PDF]
Introduction : Cochlear implantation (CI) has been reported to negatively effect on the vestibular function. The study of the vestibular function has variably been conducted by different types of diagnostic tools. The combined use of modern, rapidly
Barbara, M+6 more
core +1 more source
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu+7 more
wiley +1 more source
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen+12 more
wiley +1 more source
Turning an ear toward the talker can enhance spatial release from masking. Here, with their head free, listeners attended to speech at a gradually diminishing signal-to-noise ratio and with the noise source azimuthally separated from the speech source by
Jacques A. Grange+5 more
doaj +1 more source
Searching for a talking face: the effect of degrading the auditory signal [PDF]
Previous research (e.g. McGurk and MacDonald, 1976) suggests that faces and voices are bound automatically, but recent evidence suggests that attention is involved in a task of searching for a talking face (Alsius and Soto-Faraco, 2011).
Kitterick, PT+4 more
core +2 more sources
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li+12 more
wiley +1 more source
“Can you hear me now?”: Insurance Coverage for Hearing Benefits in the United States [PDF]
Public and private insurance coverage for hearing benefits underscores the gaps in coverage for treating hearing loss in the U.S. The commodification of the hearing benefits sector of healthcare in this country has detrimental consequences for personal ...
Whipple, Reegan
core +1 more source
The right information may matter more than frequency-place alignment: Simulations of frequency-aligned and upward shifting cochlear implant processors for a shallow electrode array insertion [PDF]
Objective: It has been claimed that speech recognition with a cochlear implant is dependent on the correct frequency alignment of analysis bands in the speech processor with characteristic frequencies (CFs) at electrode locations.
Faulkner, A, Norman, C, Rosen, S
core +1 more source