Results 91 to 100 of about 364,009 (158)

Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment

open access: yesOtolaryngology–Head and Neck Surgery, Volume 175, Issue 5, Page 1165-1168, November 2026.
Abstract The FDA approval of Otarmeni, an AAV‐based gene therapy for biallelic OTOF‐associated sensorineural hearing loss, represents a conceptual shift in otology: from bypassing defective auditory physiology to restoring it. Unlike cochlear implantation, which circumvents damaged sensory structures, OTOF gene replacement targets a synaptic deficit in
Jazlyn A. Selvasingh, Justin R. Shinn
wiley   +1 more source

Can cochlear implantation improve neurocognition in the aging population?

open access: yes, 2018
Christiane Völter,1 Lisa Götze,1 Stefan Dazert,1 Michael Falkenstein,2,3 Jan Peter Thomas1 1Department of Otorhinolaryngology, Head and Neck Surgery, Ruhr University Bochum, St.
Götze L   +4 more
core  

Recent Advances in Cochlear Implantation

open access: yes
Since the inception of cochlear implantation, the field of technological advancements associated with cochlear implantation has continued to evolve, providing patients with sensorineural hearing loss access with greater sound appreciation capabilities ...
Breanna Corle   +6 more
core   +1 more source

Effect of Case Variation on Mastoidectomy Training Using 3D‐Printed Temporal Bones Models—A Prospective, Randomized Trial

open access: yesOtolaryngology–Head and Neck Surgery, Volume 175, Issue 5, Page 1065-1074, November 2026.
Abstract Objective To investigate effects of repeated training with anatomically varied versus identical 3D‐printed models on skill acquisition, cognitive load, and skill retention in novice mastoidectomy trainees. Study Design A prospective, randomized, controlled, educational trial conducted April to September 2024 including a 3‐month retention test.
Adam Omari   +4 more
wiley   +1 more source

Uncovering the Genetic Landscape of Pediatric Hearing Loss Along the Texas–Mexico Border

open access: yesClinical Genetics, Volume 110, Issue 5, Page 627-636, November 2026.
Project GIVE provided evaluations and genome sequencing to 23 children with hearing loss along the Texas–Mexico border. Seventy percent received a molecular diagnosis and 56% of those diagnosed had changes to medical management. In this region, underdiagnosis of genetic hearing loss is due to care barriers rather than lower genetic burden.
Desiree Lanehart   +17 more
wiley   +1 more source

Effects of Delayed Language Exposure on the Language Neural Network

open access: yesLanguage and Linguistics Compass, Volume 20, Issue 6, November/December 2026.
ABSTRACT Deaf individuals are uniquely vulnerable to language deprivation—chronic lack of access to robust and reliable linguistic input during early development—which has wide‐ranging consequences for language, cognition, and neural processing throughout the lifespan.
Brennan Terhune‐Cotter, Karen Emmorey
wiley   +1 more source

Sound‐offset encoding is related to speech‐in‐noise perception at sentence level in older adults

open access: yesThe Journal of Physiology, Volume 604, Issue 21, Page 8767-8780, 1 November 2026.
Abstract figure legend Schematic summary of the study investigating sound‐onset and offset sensitivity in the brain of older adults. EEG responses to white‐noise bursts were recorded to examine neural encoding of sound onset and offset during passive listening and active task conditions.
Hasan Colak   +6 more
wiley   +1 more source

Tonotopically distinct OFF responses arise in the mouse auditory midbrain following sideband suppression

open access: yesThe Journal of Physiology, Volume 604, Issue 21, Page 8817-8840, 1 November 2026.
Abstract figure legend Sounds of different frequencies elicit spatially distinct patterns of neural activity within the inferior colliculus aligned to the tonotopic organization of afferent projections. Sound‐evoked neural responses can be visualized in awake mice that express fluorescent Ca2+ sensors.
Patrick D. Parker   +2 more
wiley   +1 more source

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