Results 241 to 250 of about 1,069,962 (387)

History of cochlear implants

open access: yesBrazilian Journal of Otorhinolaryngology, 2015
openaire   +4 more sources

Advances in Microfluidic Cochlea‐On‐A‐Chip

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen   +10 more
wiley   +1 more source

Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang   +11 more
wiley   +1 more source

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang   +8 more
wiley   +1 more source

Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation. [PDF]

open access: yesAdv Sci (Weinh)
Ren L   +15 more
europepmc   +1 more source

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