Results 191 to 200 of about 16,588 (261)

Functional reassessment of extended splice region variants in MYO7A with hearing loss and Usher syndrome

open access: yesThe Journal of Pathology, Volume 269, Issue 2, Page 222-231, June 2026.
Abstract MYO7A is a causal gene, underlying Usher syndrome type 1B (USH1B) and both autosomal recessive (DFNB2) and dominant (DFNA11) non‐syndromic hearing loss. Despite the large number of reported MYO7A variants (over 2,200), variants located in an extended splice region remain difficult to interpret and are often classified as variants of uncertain ...
Tao Shi   +5 more
wiley   +1 more source

Feasibility of Minimally Invasive Robot‐Assisted Retrofacial Access to the Stapedius Muscle for Applications in Objective Cochlear Implant Fitting: A Cadaveric Study

open access: yesThe International Journal of Medical Robotics and Computer Assisted Surgery, Volume 22, Issue 3, June 2026.
ABSTRACT Background Accurate setting of maximum comfort levels (MCL) during cochlear implant (CI) fitting is essential but subjective, especially in non‐cooperative patients. The stapedius reflex (SR) correlates with the MCL and offers an objective measure.
Dirk Arnold   +4 more
wiley   +1 more source

Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions

open access: yesSensory Neuroscience, Volume 2, Issue 2, June 2026.
ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang   +7 more
wiley   +1 more source

Progress On Sensorineural Hearing Loss: Mechanisms and Therapies

open access: yesSensory Neuroscience, Volume 2, Issue 2, June 2026.
ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang   +9 more
wiley   +1 more source

From Hearing Aid Uptake to Hearing Aid Effectiveness: Rethinking Dementia Risk Reduction in Adults With Hearing Loss

open access: yesSensory Neuroscience, Volume 2, Issue 2, June 2026.
ABSTRACT Hearing loss is a leading modifiable risk factor for dementia, yet evidence that hearing interventions reduce dementia risk has been mixed and difficult to translate into practice. Jiang and colleagues address this gap by shifting the focus from hearing aid uptake to hearing aid effectiveness in a pooled analysis of 61,089 adults with hearing ...
Bamini Gopinath   +2 more
wiley   +1 more source

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