Results 21 to 30 of about 24,567 (236)

Nicotine induced ototoxicity in rat cochlear organotypic cultures

Translational Neuroscience, 2021
Epidemiological evidence has shown that smoking is associated with an increased risk of hearing loss. However, the underlying mechanisms regarding the impact of nicotine on the cochlea remain unclear. This study aimed to investigate the cytotoxic effects
Zhao Yi, Liang Yue, Pan Chunchen, Tang Xiaomin, Sun Yuxuan, Xu Chenyu, Sun Jiaqiang, Sun Jingwu   +7 more
doaj   +1 more source

Multiplex immunohistochemistry reveals cochlear macrophage heterogeneity and local auditory nerve inflammation in cisplatin-induced hearing loss

Frontiers in Neurology, 2022
Inner ear macrophages play a vital role in cochlear homeostasis. Recent studies have demonstrated the existence of macrophages at different sites of the cochlea, with increased cochlear infiltration as an inflammatory response mechanism to injury ...
Mai Mohamed Bedeir, Yuzuru Ninoyu, Takashi Nakamura, Takahiro Tsujikawa, Shigeru Hirano   +4 more
doaj   +1 more source

Auditory cortex basal activity modulates cochlear responses in chinchillas. [PDF]

PLoS ONE, 2012
BACKGROUND: The auditory efferent system has unique neuroanatomical pathways that connect the cerebral cortex with sensory receptor cells. Pyramidal neurons located in layers V and VI of the primary auditory cortex constitute descending projections to ...
Alex León, Diego Elgueda, María A Silva, Carlos M Hamamé, Paul H Delano   +4 more
doaj   +1 more source

STEREOLOGICAL ANALYSIS OF THE COCHLEAR NUCLEI OF MONKEY (MACACA FASCICULARIS) AFTER DEAFFERENTATION

Image Analysis and Stereology, 2011
The cochlear nuclei (CN) in the brainstem receive the input signals from the inner ear through the cochlear nerve, and transmit these signals to higher auditory centres. A variety of lesions of the cochlear nerve cause deafness.
Ana M Insausti, Ricardo Insausti, Luis M Cruz-Orive, Manuel Manrique   +3 more
doaj   +1 more source

Corticofugal modulation of peripheral auditory responses

Frontiers in Systems Neuroscience, 2015
The auditory efferent system originates in the auditory cortex and projects to the medial geniculate body, inferior colliculus, cochlear nucleus and superior olivary complex reaching the cochlea through olivocochlear fibers.
Gonzalo eTerreros, Paul Hinckley Delano, Paul Hinckley Delano   +2 more
doaj   +1 more source

Cochlear nerve canal stenosis: Association with the TECTA gene

Otolaryngology Case Reports
Introduction: Cochlear nerve canal stenosis is characterized by a cochlear nerve canal measured to be less than 1.5mm on high resolution computerized tomography (HRCT) of the temporal bones.
Beilei Duan, Line Wang, Si Zhang, Zhen Zhu, Wenrui Zheng, Benjamin Heifetz, Kevin A. Peng   +6 more
doaj   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Myelination of the Postnatal Mouse Cochlear Nerve at the Peripheral-Central Nervous System Transitional Zone

Frontiers in Pediatrics, 2013
In the nerve roots of vertebrates, the peripheral nervous system (PNS) and central nervous system (CNS) interface at the PNS-CNS transitional zone (PCTZ), which consists of cell boundaries with various myelin components.
Jue eWang, Baofu eZhang, Hui eJiang, Hui eJiang, Lei eZhang, Danzheng eLiu, Danzheng eLiu, Xiao eXiao, Hannah eMa, Xuemei eLuo, Xuemei eLuo, Dennis eBojrab II, Zhengqing eHu   +12 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source