Results 141 to 150 of about 23,205 (193)

Distinct roles of chronotype, daytime napping, and sleep duration in biological and functional aging: a univariable and multivariable Mendelian randomization study. [PDF]

Clin Epigenetics
Zhang Z, Wang X, Qiu H, Luo Q, Jiang C, Yang G.   +5 more
europepmc   +1 more source

Systematic review and meta analysis of comprehensive community initiatives on alcohol use and related harms

Addiction, EarlyView.
Abstract Background and aims Comprehensive community initiatives (CCI) are prioritised in global drug strategies to address alcohol related harms. However, their impact is unclear and moderators of impact are rarely considered. We explored CCIs that address alcohol use or related harms including approaches, effectiveness and factors that strengthen ...
Peter Gates, Emily Deans, Thomas Santo Jr., Sara Farnbach   +3 more
wiley   +1 more source

Causal associations between antibody-mediated immune responses to infectious agents and cardiovascular inflammatory diseases: A Mendelian randomization study based on UK Biobank and FinnGen. [PDF]

Hum Vaccin Immunother
Huang Q, Pan W, Sun S, Chen W, Lin J.
europepmc   +1 more source

The impact of harm reduction interventions on injection‐related bacterial infections among people who inject drugs: A systematic review

Addiction, EarlyView.
Abstract Background and aims Injection‐related bacterial infections represent a major but under‐recognised health issue among people who inject drugs (PWID). Harm reduction interventions (HRIs) like needle and syringe programmes (NSP) and opioid agonist treatment (OAT) could mitigate their burden.
Anthony Cousien, Lobna Tijani, Nadia Hachicha, Manon Godart, Mathieu Castry, Karen Champenois, Perrine Roux, Sylvie Deuffic‐Burban   +7 more
wiley   +1 more source

Pharmacological sedation strategies for therapeutic gastrointestinal endoscopy: a systematic review and network meta-analysis of randomised controlled trials. [PDF]

Front Pharmacol
Jiang H, Xie Y, Qin X, Liu Q, Zhang Y, Ge C, Mamtili I.   +6 more
europepmc   +1 more source

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Evaluating Large Language Models for Automated Evidence Synthesis in Neuroimaging AI: A Multi-Model Benchmark. [PDF]

J Clin Med
Sulaimanov U, Sanlier N, Moniri A, Demir B, Serikkanov Y, Bayramoglu AR, Al-Jebur MS, Sanlier MY, Erginoglu U, Otles E, Ammanuel SG, Keles A, Erginoglu U, Baskaya MK.   +13 more
europepmc   +1 more source

SIEDY Diagnostic Accuracy in Assessing Erectile Dysfunction in Young Men Living With HIV

Andrology, EarlyView.
ABSTRACT Background Erectile dysfunction (ED) is a multidimensional condition commonly affecting men living with HIV. The structured interview of erectile dysfunction (SIEDY) is the only validated tool assessing organic, relational, and psychological factors contributing to ED, while dynamic penile color Doppler ultrasound (dPCDU) is a reliable method ...
Giorgio Tiecco, Federico Cesanelli, Cosimo Colangelo, Marco Di Gregorio, Andrea Delbarba, Paolo Facondo, Matteo Riva, Carlo Cappelli, Emanuele Focà, Francesco Castelli, Eugenia Quiros‐Roldan   +10 more
wiley   +1 more source

Molecular Tumor Boards clinical impact on patient care and structural features: A systematic review and meta-analysis. [PDF]

PLoS Med
Russo L, Giacobini E, Lentini N, Osti T, Kamal M, Boccia S, Pastorino R.   +6 more
europepmc   +1 more source

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source