Results 171 to 180 of about 25,534 (196)

Macrophage Lipid Homeostasis Drives IVDD via a Senescence‐Dependent Impairment of Efferocytosis

Cell Proliferation, EarlyView.
Intervertebral disc degeneration (IVDD) has been a leading cause of low back pain and lacks disease‐modifying therapies. Although dysregulated disc lipid metabolism is implicated, its impact on the immune microenvironment, particularly macrophages, remains unknown.
Jinyu Wang, Shiyong Ling, Qi Wang, Xuege Qiao, Jianpeng Xing, Siyang Ji, Linhui Han, Chen Yan, Zhishen Niu, Lei Yuan, Baolian Zhao, Kaiqiang Sun, Jiangang Shi   +12 more
wiley   +1 more source

Genetic Evidence for a Putative B Cell-Cholate Immunometabolic Axis in Pericarditis: A Mendelian Randomization Study. [PDF]

Biomedicines
Zhang Y, Yang W, Li X.
europepmc   +1 more source

Semiological features of epilepsy seizures and paroxysmal non‐epileptic events in children: A systematic review and meta‐analysis

Developmental Medicine &Child Neurology, EarlyView.
Pediatric paroxysmal non‐epileptic events (PNEs) are frequently misdiagnosed as epilepsy. We systematically reviewed and synthesized 40 studies, including 3123 video‐EEG monitored pediatric patients. Epileptic seizures in infants (1 month–3 years) typically presented as arrest, while in children and adolescents (1 month–21 years) they manifested as ...
Tímea Lőrincz‐Molnár, Márk Viktor Hernádfői, Krisztina Szalkay, Réka Tóth, Marie Anne Engh, Péter Kiss, Miklós Garami, Péter Hegyi, András Fogarasi   +8 more
wiley   +1 more source

Diagnostic capability of large language models in critically ill patients: a prospective single-centre study comparing ChatGPT, Claude, and Gemini with emergency physicians. [PDF]

BMC Emerg Med
Günaydın İ, Yılmaz M, Akpunar S, Karaman T, Şahin AS, İmamoğlu M, Karaca Y, Paslı S.   +7 more
europepmc   +1 more source

Prenatal exposure to paracetamol and the risk of autism and attention‐deficit/hyperactivity disorder: An umbrella review and meta‐meta‐analysis

Developmental Medicine &Child Neurology, EarlyView.
This meta‐meta‐analysis synthesizes evidence on prenatal paracetamol exposure and neurodevelopmental outcomes. Crude analyses suggest small associations with autism and ADHD, but these attenuate substantially when restricting to high‐quality meta‐analyses and low‐bias primary studies.
Hoda Tayebi‐Hillali, María Blanco‐Suárez, Berta Rivas‐Mundiña, Jacobo Limeres‐Posse, Márcio Diniz‐Freitas, Pedro Diz‐Dios   +5 more
wiley   +1 more source

Efficacy of desmopressin in reducing post-procedural bleeding among chronic kidney disease patients: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Sirilertmekasakul C, Jindasakchai P, Sorasuchart S, Lertussavavivat T, Isaranuwatchai S.   +4 more
europepmc   +1 more source

Effectiveness of Adding GLP‐1 Receptor Agonists to SGLT2 Inhibitor Therapy in Chronic Kidney Disease: A Population Based Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Individually, sodium–glucose co‐transporter‐2 inhibitors (SGLT2i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have been shown to reduce major kidney and cardiovascular events in patients with chronic kidney disease (CKD). However, evidence supporting combined GLP‐1RA and SGLT2i therapy in this population remains limited.
Hussain Salim, Shaheer Qureshi, Gaurav S. Gulsin, Habib R. Khan, Saad Ahmed Waqas, Gerry P. McCann, Amit Garg, Mohammed Shurrab, Kamlesh Khunti, Muhammad Rashid   +9 more
wiley   +1 more source

Elevated Neutrophil Count as a Causal Risk Factor for Endometriosis: A Mendelian Randomization Study. [PDF]

Int J Womens Health
Li M, Zhou X, Chen Y.
europepmc   +1 more source

Diagnosis and Management of Adult Type 1 Diabetes Mellitus: Systematic Reviews of Biomarkers, Insulin Regimens and Insulin Delivery Devices Highlighting Evidence Gaps in Emergency and Humanitarian Settings

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Supporting the World Health Organization's (WHO) 2021 Global Diabetes Compact's goals, we conducted three systematic reviews on type 1 diabetes (T1D) in adults concerning (1) diagnostic biomarkers, (2) insulin regimens and (3) insulin delivery devices, focusing on emergency and humanitarian settings.
Niyati Patwa, Alexandria Bennett, Nicole Shaver, Lama Dahroug, Becky Skidmore, Shannon E. Kelly, George Wells, Andrea C. Tricco, Heather Lochnan, Julian Little, Melissa Brouwers   +10 more
wiley   +1 more source

A cross-sectional evaluation of large language model chatbot interfaces for patient-facing herpes zoster information: safety, information quality, and readability. [PDF]

Front Public Health
Liang D, Mai C, Zhang Z, Lin J, Wu X, Lu H, Shang J, Wang H, Li H.   +8 more
europepmc   +1 more source