Results 61 to 70 of about 1,712,853 (285)
We systematically reviewed conversion therapy for esophageal squamous cell carcinoma and propose a response‐based treatment strategy for cT4b and M1 disease. For cT4b, we emphasize definitive chemoradiotherapy with timed re‐evaluation and selective salvage or chemoselection to surgery; for M1, conversion is reserved for limited‐burden responders with ...
Eisuke Booka, Hiroya Takeuchi
wiley +1 more source
Total Neoadjuvant Therapy for Rectal Cancer: Why Japan Says “Not Yet”
ABSTRACT Total neoadjuvant therapy (TNT) has rapidly gained global acceptance as a standard treatment for locally advanced rectal cancer (LARC). Supported by multiple phase III trials, TNT improves pathological complete response (pCR) rates, enhances systemic control, and expands opportunities for non‐operative management (NOM).
Kay Uehara +4 more
wiley +1 more source
Background Systematic reviews (SRs) of randomized controlled trials (RCTs) are considered one of the most reliable study types. Through a systematic and thorough literature search, researchers aim to collect all research relevant to their purpose.
Martin Nørregård Eybye +3 more
doaj +1 more source
GLIM‐defined malnutrition probably worsens overall survival in patients with gastroenterological cancer after surgery. ABSTRACT Background In cancer patients, malnutrition worsens postoperative outcomes, with increased complications and poor prognosis.
Ryota Matsui +4 more
wiley +1 more source
Background Cochrane primarily aims to systematically review trials of effectiveness that are important to inform clinical decisions. Editorial groups support authors to achieve high-quality reviews and prioritise review proposals in their clinical domain
Jasmin Alloo +5 more
doaj +1 more source
The Cochrane Library and Autism Spectrum Disorder: An Overview of Reviews
Danielle M Wheeler +3 more
openalex +3 more sources
This systematic review and meta‐analysis evaluated the role of primary tumor resection (PTR) in asymptomatic patients with unresectable metastatic colorectal cancer. Across 17 eligible studies including 9317 patients, PTR did not improve overall or progression‐free survival compared with chemotherapy alone.
Junpei Takashima +3 more
wiley +1 more source
Minimally invasive anatomic liver resection (AR) including major hepatectomy and liver parenchyma‐sparing AR is technically complex and demanding. This systematic review with meta‐analysis including 15 studies comparing 2042 robotic AR and 2129 laparoscopic AR patients demonstrated largely comparable perioperative outcomes and partly better outcomes ...
Yutaro Kato +3 more
wiley +1 more source
Conservative treatment of acute knee osteoarthritis: A review of the Cochrane Library
Objective: To analyze conservative treatment of knee pain in patients with osteoarthritis. Methods: A Cochrane Library search related to knee osteoartritis was analyzed.
Emerito Carlos Rodriguez-Merchan
doaj +1 more source
This summary is based on a Cochrane Review previously published in the Cochrane Database of Systematic Reviews 2020, Issue 7, Art. No.: CD012554, DOI: 10.1002/14651858.CD012554.pub2 (see www.cochranelibrary.com for information).
William Levack
doaj +1 more source

