Results 191 to 200 of about 133,391 (266)

Effectiveness, acceptability, adherence, and safety of exergaming for depressive symptoms: a systematic review and meta-analysis. [PDF]

NPJ Digit Med
Tang D, Liu C, Liu J, Liu T, Ma R, Sum KR.   +5 more
europepmc   +1 more source

Health Care Policy Implementation Trial of Primary Human Papillomavirus–Based Cervical Screening in Denmark

International Journal of Cancer, EarlyView.
Uncertainty has persisted over whether human papillomavirus (HPV) testing outperforms high‐quality cytology in real‐world cervical cancer screening programs. To address this, Denmark launched a nationwide trial in 2021, implementing an HPV‐based screening strategy using specialized algorithms integrated with molecular and cytology triage to optimize ...
Jesper Bonde, Jeppe Bennekou Schroll, Birgitte Tønnes Pedersen, Elsebeth Lynge, Marianne Waldstrøm, Petra Hall Viborg, Anna Frandsen, Rikke Holst Andersen, Susanne Nielsen, Doris Schledermann, Bettina Kjær Kristensen, Berit Andersen, on behalf of the National Danish Cervical Cancer Screening Steering Committee   +12 more
wiley   +1 more source

Systematic review on the safety and efficacy of immune checkpoint inhibitors combined with stereotactic body radiotherapy in advanced pancreatic cancer. [PDF]

Clin Exp Med
Magashi MA, Danbala IA, Shaibu Z, Abdullahi MM, Cai H.   +4 more
europepmc   +1 more source

Indirect Comparison of Neoadjuvant Treatment Strategies for Muscle‐Invasive Bladder Cancer: ddMVAC and Perioperative Durvalumab‐Gemcitabine‐Cisplatin Versus Gemcitabine‐Cisplatin: A Systematic Review and Network Meta‐Analysis of Randomised Controlled Trials

International Journal of Cancer, EarlyView.
Optimizing neoadjuvant therapy for muscle‐invasive bladder cancer patients who are eligible for cisplatin remains difficult, owing particularly to high toxicity and recurrence rates. This meta‐analysis compared dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) against durvalumab plus gemcitabine‐cisplatin (D‐GC) and GC alone ...
Maurin Helen Mangold, Gloria Baumann, Victoria Luise Simone Wieland, Nicolas Carl, Luisa Vivienne Renner, Alexander Studier‐Fischer, Hanna Menold, Stefanie Zschäbitz, Frederik Wessels, Niklas Westhoff, Maurice Stephan Michel, Karl‐Friedrich Kowalewski, Caelán Max Haney‐Aubert   +12 more
wiley   +1 more source

Heterogeneity in Histological Evaluation of Microscopic Colitis in Randomized Clinical Trials: An Umbrella Review. [PDF]

Inflamm Bowel Dis
Yuan Y, Kerchove KV, Ma C, Verstockt B, Nardone OM, Bernstein CN, Munch A, Jairath V.   +7 more
europepmc   +1 more source

Risk–Benefit of Phase 2 Monotherapy Trials in Adult Solid Cancers: A Systematic Review and Meta‐Analysis

International Journal of Cancer, EarlyView.
The therapeutic status of drug administration in phase 2 cancer trials is ambiguous, as these studies test efficacy without strong evidence of clinical benefit. Nonetheless, patients face meaningful risks. This review compared efficacy and safety of monotherapy drugs in phase 2 and phase 3 trials across six cancer types.
Charlotte Ouimet, Monica Rosu, Jonathan Kimmelman   +2 more
wiley   +1 more source

Global prevalence and risk of gastroesophageal reflux disease symptoms in pregnancy: a systematic review and meta-analysis. [PDF]

BMC Pregnancy Childbirth
Khurmatullina AR, Andreev DN, Maev IV, Lyamina SV, Kucheryavyy YA, Beliy PA, Sokolov FS.   +6 more
europepmc   +1 more source

The Addition of Concurrent Immune Checkpoint Inhibitors for Chemoradiotherapy With Consolidative Immune Checkpoint Inhibitors in Unresectable Cancers: A Systematic Review and Meta‐Analysis

International Journal of Cancer, EarlyView.
Currently, there are at least 30 ongoing clinical trials in the enrollment phase to evaluate adding concurrent ICIs to the PACIFIC regimen for a variety of solid tumors. Considering the lack of head‐to‐head comparative studies, this meta‐analysis aims to investigate the differences in efficacy between adding and not adding concurrent ICIs to CRT ...
Xu Tong, Zhenting Liu, Xiaoxiang Zhou, Nan Bi, Yibo Gao   +4 more
wiley   +1 more source

Obstetrics and gynecology devices designed for low‐ and middle‐income countries: A narrative review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 71-80, April 2025.
Abstract There are many barriers contributing to poor health outcomes for women in low‐ and middle‐income countries (LMICs), one of which is the lack of necessary medical devices. Presently, the development of various kinds of devices intended to improve women's health outcomes specifically in LMICs remains underrepresented in the literature; therefore,
Dhanalakshmi Thiyagarajan, Enaam A. Adanu, K. Rivet Amico   +2 more
wiley   +1 more source

RoBuster-Corpus Annotated With Risk of Bias Text Spans in Randomized Controlled Trials in Physiotherapy and Rehabilitation: Corpus Development and Annotation Study. [PDF]

JMIR Form Res
Dhrangadhariya A, Hilfiker R, Sattelmayer KM, Naderi N, Giacomino K, Caliesch R, Higgins J, Marchand-Maillet S, Müller H.   +8 more
europepmc   +1 more source