Results 91 to 100 of about 80,955 (266)
THE NUTRITIONAL EDUCATION OF YOUTH – A BASIC ELEMENT OF AN OPTIMAL HEALTH
Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae, 2016 The fact that one of the pillars of a good health is optimal nutrition. For this reason, knowing what, how, when and how much to eat becomes a fundamental question.
Paula DROSESCU +2 more
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The Budgetary and Economic Impact of Taxation in the Member States of the European Union [PDF]
Global Economic ObserverFiscal policy is a key strategic instrument in the European macroeconomic framework, serving a dual role: as the primary source of public revenue and as a mechanism for countercyclical intervention, redistribution, and the correction of market failures ...
ALEXANDRU-IONUȚ ROGOVEANU +1 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Financial Structure, Profitability and Productivity in the Romanian Pharmaceutical Industry: A 2020–2024 Analysis [PDF]
Global Economic ObserverThe pharmaceutical manufacturing sector is one of the most stable and high-performing sectors of the Romanian economy. This study analyzes the evolution of the financial performance of companies classified under NACE code 2120 (Manufacture of ...
MARIA ZENOVIA GRIGORE +1 more
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source