Results 321 to 330 of about 808,904 (392)

COD Plan

Draft of the COD (Communication, Outreach, Dissemination ...
openaire   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Sequencing effects of balance and change of direction training on physical fitness in young male and highly trained soccer players. [PDF]

Sci Rep
Aliani L, Hammami R, Sortwell A, Selmi W, Rebai H, Granacher U.   +5 more
europepmc   +1 more source

Liver development in Atlantic cod (Gadus morhua L.) larvae: Histomorphological analysis of biliary ABC transporters and hepatic vacuolization. [PDF]

Fish Physiol Biochem
Marthinsen JL, Reitan KI, Kjørsvik E, Bardal T, Li K, Nunes B, Vassbotn AM, Olsen RE.   +7 more
europepmc   +1 more source

Cost and Carbon Implications of Industrial Organic Load Reduction across Water Resource Recovery Facility Typologies. [PDF]

Environ Sci Technol
Rai S, Zhang X, Wright NC, Arnold WA, Novak PJ, Guest JS.   +5 more
europepmc   +1 more source

Northern cod spawning sites in 2015

Rose, George
openalex   +1 more source

Sugarcane Vinasse and Glycerol as Potential Carbon Sources for Sulfate-Rich Wastewater Treatment: Mitigating the Impacts of Acid Mine Drainage. [PDF]

ACS Omega
Nogueira EW, Godoi LAG, Couto PT, Carneiro RB, Takeda PY, Cunha MP, Zampieri BDB, Brucha G, Damianovic MHRZ.   +8 more
europepmc   +1 more source

Determinants of agility across biological maturation status in soccer players. [PDF]

BMC Sports Sci Med Rehabil
Ito H, Hirayama K, Naito Y, Akama T.
europepmc   +1 more source