Results 131 to 140 of about 1,735,552 (292)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
epkanol/governing-commons-code-clones: Initial submission
<p>First release at article submission</p> <p>Thanks to @andreas-bauer for reporting and fixing PR#1 for the version updates - will have to think about whether we should be explicit with versions in the Dockerfile, or just document them,
Andreas Bauer, epkanol
core +1 more source
Code clones in feature-oriented software product lines
, 2010 Some limitations of object-oriented mechanisms are known to cause code clones (e.g., extension using inheritance). Novel programming paradigms such as feature-oriented programming (FOP) aim at alleviating these limitations.
Christian Kästner +2 more
core +1 more source
Радіоелектронні і комп'ютерні системиThe article’s subject matter deals with the management of software clones. Software clones are duplicate code fragments that can exist in the same or different software files. Software clone detection and management has become a well-established research
Manpreet Kaur +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
USING MACHINE LEARNING METHODS IN SOFTWARE CLONE DETECTION
Безопасность информационных технологийThe article is devoted to the analysis of methods for determining the similarity of software code fragments, particularly at the level of binary representations.
Nikita A. Gribkov, Denis V. Ivanov
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Mashail8/Code-Smells: Code Smell Taxonomy Research Materials
<p>Code Smell Taxonomy Research Materials</p> <p>This repository contains the materials used in the research study "A Novel Taxonomy to Capture Code Smells Caused by Refactoring".</p> <p>Contents</p> <p>
Code Smell Dataset
core +1 more source
Relation of code clones and change couplings
, 2006 . Code clones have long been recognized as bad smells in software systems and are considered to cause maintenance problems during evolution. It is broadly assumed that the more clones two files share, the more often they have to be changed together. This
Beat Fluri +3 more
core +1 more source