Results 101 to 110 of about 4,221,254 (369)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Static Verification of Linux Kernel Configurations

open access: yesТруды Института системного программирования РАН, 2018
The Linux kernel is often used as a real world case study to demonstrate novel software product line engineering research methods. It is one of the most sophisticated programs nowadays.
S. V. Kozin, V. S. Mutilin
doaj   +1 more source

The Affordable Care Act’s (ACA) Employer Shared Responsibility Determination and the Potential ACA Employer Penalty [PDF]

open access: yes, 2015
[Excerpt] The Patient Protection and Affordable Care Act (ACA; P.L. 111-148, as amended) expands insurance coverage in the United States through its “shared responsibility” provisions: Employers either provide health coverage or face potential employer ...
Whittaker, Julie
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Використання ВПЗ в процесі розробки ПЗ [PDF]

open access: yes, 2015
The paper describes which free instruments can be used during development process and for what this instruments is used. There is a large number of such software to measure code quality, collect project metrics, build code coverage statistics, manage ...
Подібка, Іван Орестович
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

A Coverage-Guided Fuzzing Method for Automatic Software Vulnerability Detection Using Reinforcement Learning-Enabled Multi-Level Input Mutation

open access: yesIEEE Access
Fuzzing is a popular and effective software testing technique that automatically generates or modifies inputs to test the stability and vulnerabilities of a software system, which has been widely applied and improved by security researchers and experts ...
Van-Hau Pham   +4 more
doaj   +1 more source

Code coverage and test suite effectiveness: Empirical study with real bugs in large systems

open access: yesIEEE International Conference on Software Analysis, Evolution, and Reengineering, 2015
During software maintenance, testing is a crucial activity to ensure the quality of program code as it evolves over time. With the increasing size and complexity of software, adequate software testing has become increasingly important.
Pavneet Singh Kochhar   +2 more
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

A Model Checking-Based Method of Functional Test Generation for HDL Descriptions

open access: yesТруды Института системного программирования РАН, 2018
Automated test generation is a promising direction in hardware verification research area. Functional test generation methods based on models are widespread at the moment.
M. S. Lebedev, S. A. Smolov
doaj   +1 more source

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