Results 61 to 70 of about 4,221,254 (369)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

On the Analysis of Coverage Feedback in a Fuzzing Proprietary System

Applied Sciences
Coverage feedback is one of the key mechanisms for improving the effectiveness of fuzzers by measuring and comparing the executed code regions while processing input data.
Daehee Jang, Jaemin Kim, Jiho Kim, Woohyeop Im, Minwoo Jeong, Byeongcheol Choi, Chongkyung Kil   +6 more
doaj   +1 more source

Code Coverage and Postrelease Defects: A Large-Scale Study on Open Source Projects

IEEE Transactions on Reliability, 2017
Testing is a pivotal activity in ensuring the quality of software. Code coverage is a common metric used as a yardstick to measure the efficacy and adequacy of testing. However, does higher coverage actually lead to a decline in postrelease bugs?
Pavneet Singh Kochhar, D. Lo, J. Lawall, N. Nagappan   +3 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

SCH-Hunter: A Taint-Based Hybrid Fuzzing Framework for Smart Contract Honeypots

Information
Existing smart contract honeypot detection approaches exhibit high false negatives and positives due to (i) their inability to generate transaction sequences triggering order-dependent traps and (ii) their limited code coverage from traditional fuzzing’s
Haoyu Zhang, Baotong Wang, Wenhao Fu, Leyi Shi   +3 more
doaj   +1 more source

CUP: Comprehensive User-Space Protection for C/C++

, 2017
Memory corruption vulnerabilities in C/C++ applications enable attackers to execute code, change data, and leak information. Current memory sanitizers do no provide comprehensive coverage of a program's data. In particular, existing tools focus primarily
Akritidis Periklis, Eigler Frank Ch, Jim Trevor, Nagarakatte Santosh, Serebryany Konstantin   +4 more
core   +1 more source

An Effective Android Code Coverage Tool

Conference on Computer and Communications Security, 2018
The deluge of Android apps from third-party developers calls for sophisticated security testing and analysis techniques to inspect suspicious apps without accessing their source code.
Aleksandr Pilgun, O. Gadyatskaya, Stanislav Dashevskyi, Yury Zhauniarovich, Artsiom Kushniarou   +4 more
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Combining dynamic symbolic execution, code static analysis and fuzzing

Труды Института системного программирования РАН, 2019
This paper describes a new approach for dynamic code analysis. It combines dynamic symbolic execution and static code analysis with fuzzing to increase efficiency of each component.
A. Yu. Gerasimov, S. S. Sargsyan, S. F. Kurmangaleev, J. A. Hakobyan, S. A. Asryan, M. K. Ermakov   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source