Results 91 to 100 of about 18,564,701 (283)
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
A redundant residue number system assisted multicarrier direct-sequence code-division dynamic multiple-access (RRNS MC/DS-CDDMA) scheme is proposed for application in cognitive radios (CRs).
Zhang, Shuo +2 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Incoherent 2D optical code division multiple access
Focuses on incoherent 2D optical code division multiple ...
Glesk, I.
core +3 more sources
Multiuser cyclic shift keying spread spectrum underwater acoustic communication
Aiming at the problem of low data rate and high receiver complexity of existing direct sequence spread spectrum code division multiple access (DS-CDMA),a novel code division multiple access (CDMA) using cyclic shift keying (CSK) signaling,namely CSK-CDMA,
Cheng-bing HE +6 more
doaj +2 more sources
Improved Hybrid MMSE Detection for Turbo Trellis Coded Modulation Assisted Multi-User OFDM Systems [PDF]
A genetic algorithm assisted minimum mean-square error (MMSE) multi-user detector (MUD) is proposed for a turbo-trellis-coded modulation-based space division multiple access aided orthogonal frequency division multiplexing system.
Jiang, M., Hanzo, L.
core +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Bipolar Optical Code Division Multiple Access Techniques Using a Dual Electro-Optical Modulator Implemented in Free-Space Optics Communications. [PDF]
Tseng SP, Wijanto E, Lai PH, Cheng HC.
europepmc +1 more source

