Results 91 to 100 of about 18,564,701 (283)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Redundant Residue Number System Assisted Multicarrier Direct-Sequence Code-Division Dynamic Multiple-Access for Cognitive Radios

open access: yes
A redundant residue number system assisted multicarrier direct-sequence code-division dynamic multiple-access (RRNS MC/DS-CDDMA) scheme is proposed for application in cognitive radios (CRs).
Zhang, Shuo   +2 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Incoherent 2D optical code division multiple access

open access: yes, 2004
Focuses on incoherent 2D optical code division multiple ...
Glesk, I.
core   +3 more sources

Multiuser cyclic shift keying spread spectrum underwater acoustic communication

open access: yesTongxin xuebao, 2017
Aiming at the problem of low data rate and high receiver complexity of existing direct sequence spread spectrum code division multiple access (DS-CDMA),a novel code division multiple access (CDMA) using cyclic shift keying (CSK) signaling,namely CSK-CDMA,
Cheng-bing HE   +6 more
doaj   +2 more sources

Improved Hybrid MMSE Detection for Turbo Trellis Coded Modulation Assisted Multi-User OFDM Systems [PDF]

open access: yes, 2004
A genetic algorithm assisted minimum mean-square error (MMSE) multi-user detector (MUD) is proposed for a turbo-trellis-coded modulation-based space division multiple access aided orthogonal frequency division multiplexing system.
Jiang, M., Hanzo, L.
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

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