Results 31 to 40 of about 214,002 (340)

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane   +11 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

CDMA/OTFS Sensing Outperforms Pure OTFS at the Same Communication Throughput

open access: yesIEEE Open Journal of Vehicular Technology
There is a dearth of publications on the subject of spreading-aided Orthogonal Time Frequency Space (OTFS) solutions, especially for Integrated Sensing and Communication (ISAC), even though Code Division Multiple Access (CDMA) assisted multi-user OTFS ...
Hugo Hawkins   +3 more
doaj   +1 more source

Multiple Access With Polarity Division Sparse Code for Visible Light Communication

open access: yesIEEE Photonics Journal, 2019
The increasing demand of mobile internet and Internet of Things poses challenging requirements for indoor wireless communication. Visible light communication (VLC) is a promising technology to alleviate the growing traffic problem. In addition, nonlinear
Yu Xiao, Zhitong Huang, Yuefeng Ji
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

General Signal Model for Multiple-Input Multiple-Output GMTI Radar

open access: yesSensors, 2018
Multiple-input multiple-output (MIMO) ground moving target indication (GMTI) radar has been studied recently because of its excellent performance. In this paper, a general signal model is established for the MIMO GMTI radar with both fast-time and slow ...
Fuyou Li   +4 more
doaj   +1 more source

6G Network Architecture Using FSO-PDM/PV-OCDMA System with Weather Performance Analysis

open access: yesApplied Sciences, 2022
This paper presents a novel 160 Gbps free space optics (FSO) communication system for 6G applications. Polarization division multiplexing (PDM) is integrated with an optical code division multiple access (OCDMA) technique to form a PDM-OCDMA hybrid ...
Mehtab Singh   +5 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Performance improvement of non-orthogonal multiple access scheme using code division multiplexing

open access: yesInternational Journal of Distributed Sensor Networks, 2017
Currently, the standardization of fifth-generation mobile communication system (5G), which realizes 10 Gbps transmission, is in progress. In mobile communications, it is generally difficult to perform high-capacity transmission because of channel fading.
Hiroki Kitagawa, Eiji Okamoto
doaj   +1 more source

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