Results 31 to 40 of about 2,043,855 (291)

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez   +14 more
wiley   +1 more source

Evaluating Coding Proficiency of Large Language Models: An Investigation Through Machine Learning Problems

open access: yesIEEE Access
Large Language Models (LLMs) have demonstrated remarkable capabilities across various domains, but their effectiveness in coding workflows, particularly in machine learning (ML), requires deeper evaluation.
Eunbi Ko, Pilsung Kang
doaj   +1 more source

Optimisations for quadrature representations of finite element tensors through automated code generation [PDF]

open access: yes, 2010
We examine aspects of the computation of finite element matrices and vectors which are made possible by automated code generation. Given a variational form in a syntax which resembles standard mathematical notation, the low-level computer code for ...
Wells, GN, Ølgaard, KB
core  

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers   +5 more
wiley   +1 more source

Prompt Learning Based Parameter-efficient Code Generation [PDF]

open access: yesJisuanji kexue
Automatic code generation is one of the effective ways to improve the efficiency of software development.Existing research often regards code generation as a sequence-to-sequence task,and the process of fine-tuning of large-scale pre-trained language ...
XU Yiran, ZHOU Yu
doaj   +1 more source

Code coverage analysis and test case generation [PDF]

open access: yes, 2018
Cílem této práce je vytvoření metody pro generování testovacích scénářů a vyhodnocení jejich effektivity. Tato metoda je vytvořená na základě analýzy konkrétního programu, která je založená na určení dopadů, jaký mají jednotlivé parametry programu na ...
Sýkora Kryštof
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

ChatGPT for Robotics: Design Principles and Model Abilities

open access: yesIEEE Access
This paper presents an experimental study regarding the use of OpenAI’s ChatGPT for robotics applications. We outline a strategy that combines design principles for prompt engineering and the creation of a high-level function library which allows ...
Sai H. Vemprala   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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