Results 41 to 50 of about 10,358,982 (263)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Computer modelling of cable reinforced membranes
Computer Assisted Methods in Engineering and Science, 2023 This paper is intended to summarise the actual work in the area of large deformations of tension systems. The previously conducted research [23, 24] adds significant contributions to the understanding of the response· characteristics of pneumatics and ...
Marek Stanuszek
doaj
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
International Building Code: 2009 [PDF]
, 2009 Manual describing best practices for constructing buildings that meet safety and energy requirements; appropriate building materials and use; and related issues: "This comprehensive building code establishes minimum regulations for building systems using
International Code Council
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2023 Code for the study "Another dimension! Using dimension weighting to observe integration and retrieval in localization performance", to-be-published in Journal of Experimental Psychology: Human Perception and Performance.
Schöpper, Lars-Michael +2 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Laporan Agustus 2018 Perpustakaan Universitas Medan Area
, 2018 41 HalamanPuji syukur kepada Allah SWT, karena atas Karunia dan Rahmat-Nya laporan bulanan Perpustakaan Universitas Medan Area Bulan Agustus 2018 dapat tersusun dengan baik.
Perpustakaan, Universitas Medan Area
core +1 more source
Frontiers in Public HealthObjectiveTo create county-, 5-digit ZIP code (ZIP-5)–, and 3-digit ZIP code (ZIP-3)–level datasets of the Social Vulnerability Index (SVI) and its components for 2016–2022 to validate the methodology beyond county level, explore trends in SVI over time ...
Carmen D. Ng, Pluto Zhang, Stacey Kowal
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source