Results 81 to 90 of about 107,111 (311)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Analisis Campur Kode dalam Tuturan Komentator pada Game Ketujuh Grand Final M5 World Championship
Prasasti: Journal of LinguisticsIn the current era of globalization, there is a lot of competition in the field of electronic sports (e-sport). In these matches there are commentators who often combine two or more languages in one speech and elements of other languages into one speech.
Sabrina Tamimi, Kundharu Saddhono
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Code‐mixing and Code‐switching
Code‐mixing and Code‐switchingCode‐mixing or code‐switching is the use of more than one language or variety within a single communication event. Various information is signaled by the choice of language or by switching from one variety to another. This may include the structure of the ongoing interaction, the relevant social context, or elements of the speakers' identities ...
openaire +1 more source
Code-Mixing in Sabah and Sarawak English Short Stories
, 2023 Yvonne Michelle Campbell +1 more
openalex +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Fiber-Mixing Codes between Shifts of Finite Type and Factors of Gibbs Measures
Entropy, 2016 A sliding block code π : X → Y between shift spaces is called fiber-mixing if, for every x and x ′ in X with y = π ( x ) = π ( x ′ ) , there is z ∈ π - 1 ( y ) which is left asymptotic to x and right asymptotic ...
Uijin Jung
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Code-Mixing in Narrative Essay of Fifth Grade Students
International Journal of Science and Applied Science: Conference Series, 2019 This study aims to find out the code-mixing in narrative essays of grade 5th primary school and what factor is behind the use of code-mixing. This study is done in one of the school in Lembang sub-district which is most of the students are coming from ...
Carolin Eninta Ginting, Rahman Rahman
doaj +1 more source