Results 131 to 140 of about 1,761,628 (300)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Lobbying the European Parliament: a necessary evil. CEPS Policy Brief No. 242, May 2011 [PDF]

open access: yes, 2011
While the European Parliament is in many ways more transparent and more accessible than many of the EU’s national parliaments, the code of conduct for lobbyists and the Parliament’s own Rules of Procedure are rather vague.
Rasmussen, Maja Kluger.
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Announcing In the Library with the Lead Pipe’s Community Code of Conduct

open access: yesIn the Library with the Lead Pipe, 2014
The Editorial Board is pleased to announce In the Library with the Lead Pipe’s adoption a Code of Conduct. By doing so, we hope to protect the members of our community from harassing behaviors in Lead Pipe spaces, including this website, our social media
Ellie Collier
doaj  

Preceitos e normas internas (kakun) de casas comerciais japonesas: um estudo sobre a longevidade e a ética da corporação japonesa

open access: yesCadernos EBAPE.BR
O estudo de corporações de uma das maiores economias mundiais se justifica em um mundo sem fronteiras no qual hoje vivemos e onde diferenças culturais afetam relações negociais.
Isao Yamamoto, Sylvia Constant Vergara
doaj   +1 more source

Quantitative Assessment of the Impact of Automatic Static Analysis Issues on Time Efficiency [PDF]

open access: yes, 2011
Background: Automatic Static Analysis (ASA) tools analyze source code and look for code patterns (aka smells) that might cause defective behavior or might degrade other dimensions of software quality, e.g. efficiency.
Morisio, Maurizio   +2 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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