Results 81 to 90 of about 523,333 (261)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Small-Group Exercise in Professionalism and Code of Ethics Development
MedEdPORTAL, 2012 This resource features a series of interprofessional small-group exercises to explore students' perceptions of the other health professions. During this 3-hour session, groups also discuss the meaning of professional behavior and use the insights gained ...
Devin Reed Nickol +6 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
BANTUAN HUKUM BAGI ANGGOTA KEPOLISIAN YANG MELAKUKAN TINDAK PIDANA PADA SIDANG KOMISI KODE ETIK
Unes Journal of Swara Justisia, 2019 A member of the National Police who allegedly violates the code of ethics of the Police profession is given the right to defend himself and get help and accompanied by a companion appointed by the Supreme Court (Ankum) originating from the Internal ...
Irwan Sukma, Otong Rosadi
doaj
Educational Psychology JournalSchool discipline compliance for students is an action that shows behavior in accordance with the norms or rules of discipline made and applied at school. School discipline compliance behavior by students can be influenced by various factors.
Andri Nur Mutaqin, Rulita Hendriyani
doaj +1 more source
The legal nature of schools, codes of conduct and disciplinary proceedings in schools
Koers : Bulletin for Christian Scholarship, 2003 All stakeholders in education should appreciate the legal nature of schools, legal provisions for the management of schools and discipline in schools as well as codes of conduct.
R. Roos
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source