Results 101 to 110 of about 2,090,361 (288)

Quantum Search-Aided Multi-User Detection for Sparse Code Multiple Access

IEEE Access, 2019
With the explosive proliferation of mobile devices, the scarcity of communication resources has emerged as a critical issue in the next generation (NG) communication systems.
Wenjing Ye, Wei Chen, Xin Guo, Chen Sun, Lajos Hanzo   +4 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

An open-source natural language processing toolkit to support software development: addressing automatic bug detection, code summarisation and code search. [PDF]

Open Res Eur, 2022
Robledo C, Sallicati F, de Chalendar G, Fernández M, de Castro P, Martín E, Gutiérrez J, Bouachera Y.   +7 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Complete permutation Gray code implemented by finite state machine

The Journal of Engineering, 2014
An enumerating method of complete permutation array is proposed. The list of n! permutations based on Gray code defined over finite symbol set Z(n) = {1, 2, …, n} is implemented by finite state machine, named as n-RPGCF.
Li Peng, Pingliang Zeng, Hao Li, Xin Li
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Understanding Code Smell Detection Through Hyperparameter Optimization and Metric Correlation Analysis

IEEE Access
Hyperparameter optimization plays a pivotal role in the reliability and generalization of machine-learning models for software quality prediction. This paper presents a comparative evaluation of three search strategies: Grid Search, Random Search, and a ...
Marcela Mosquera, Rodolfo Bojorque, Pamela Flores   +2 more
doaj   +1 more source

Dynamic stacking ensemble for cross-language code smell detection [PDF]

PeerJ Computer Science
Code smells refer to poor design and implementation choices by software engineers that might affect the overall software quality. Code smells detection using machine learning models has become a popular area to build effective models that are capable of ...
Hamoud Aljamaan
doaj   +2 more sources