Results 141 to 150 of about 198,004 (302)
Relational bulk reconstruction from modular flow
The entanglement wedge reconstruction paradigm in AdS/CFT states that for a bulk qudit within the entanglement wedge of a boundary subregion A ¯ $$ \overline{A} $$ , operators acting on the bulk qudit can be reconstructed as CFT operators on A ...
Onkar Parrikar +3 more
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Application of Fuzzy Set Theory in Option of Response Spectra
In order to consider the fuzziness of seismic intensity indecated by zoning map and seismic code in seismic design of structure, an innovative method in option of design spectrum in consideration of fuzziness of regional seismic hazard and site condition
Jingyu, Su, Xiyuan, Zhou
core
An integral approach to plasma-wall interaction modelling for EU-DEMO
An integral approach to plasma-wall interaction (PWI) modelling for DEMO is presented, which is part of the EUROfusion Theory and Advanced Simulation Coordination activities that were established to advance the understanding and predictive capabilities ...
D. Matveev +22 more
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Executing Gödel’s programme in set theory [PDF]
The study of set theory (a mathematical theory of infinite collections) has garnered a great deal of philosophical interest since its development. There are several reasons for this, not least because it has a deep foundational role in mathematics ...
Barton, Neil
core
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source

