Results 41 to 50 of about 198,004 (302)
Nuclear Engineering and Technology, 2013 MAAP4 is a computer code that can simulate the response of a light water reactor power plant during severe accident sequences, including actions taken as part of accident management.
KEVIN ROBERTS, ROBERT SANDERS
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
, 2023 This case study is based on a research project that analyzed how expert evaluators combine different modes of thinking when screening ideas for innovation. The findings of this research project are detailed in the journal article, “How experts screen ideas: the complex interplay of intuition, analysis and sensemaking” by Sukhov et al.
Sukhov, Alexandre, Sihvonen, Antti
openaire +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2008 The(frequently updated) original version is avalable at http://www.scholarpedia.org/article/Sparse_codingMammalian brains consist of billions of neurons, each capable of independent electrical activity.
Endres, D M +3 more
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Design of Low-Density Parity-Check Code Pair for Joint Source-Channel Coding Systems Based on Graph Theory [PDF]
, 2023 In this article, a graph-theoretic method (taking advantage of constraints among sets associated with the corresponding parity-check matrices) is applied for the construction of a double low-density parity-check (D-LDPC) code (also known as LDPC code ...
Jiguang He +7 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Attack of the clones: an investigation into removing redundant source code [PDF]
, 2002 Long-term maintenance of code will often lead to the introduction of duplicated or 'cloned' code. Legacy systems riddled with these clones have large amounts of redundant code and are more difficult to understand and maintain.
Bailey, John Oliver
core