Results 71 to 80 of about 2,148,225 (286)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Decompositions of factor codes and embeddings between shift spaces with unequal entropies

, 2012
Given a factor code between sofic shifts X and Y, there is a family of decompositions of the original code into factor codes such that the entropies of the intermediate subshifts arising from the decompositions are dense in the interval from the entropy ...
Adler, Boyle, IN-JE LEE, SOONJO HONG, UIJIN JUNG   +4 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Conditional resolvability in graphs: a survey

International Journal of Mathematics and Mathematical Sciences, 2004
For an ordered set W={w1,w2,…,wk} of vertices and a vertex v in a connected graph G, the code of v with respect to W is the k-vector cW(v)=(d(v,w1),d(v,w2),…,d(v,wk)), where d(x,y) represents the distance between the vertices x and y.
Varaporn Saenpholphat, Ping Zhang
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Enrichment of Circular Code Motifs in the Genes of the Yeast Saccharomyces cerevisiae

Life, 2017
A set X of 20 trinucleotides has been found to have the highest average occurrence in the reading frame, compared to the two shifted frames, of genes of bacteria, archaea, eukaryotes,
Christian J. Michel, Viviane Nguefack Ngoune, Olivier Poch, Raymond Ripp, Julie D. Thompson   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Algebraic Linear Analysis for Number Theoretic Transform in Lattice-Based Cryptography

Transactions on Cryptographic Hardware and Embedded Systems
The topic of verifying postquantum cryptographic software has never been more pressing than today between the new NIST postquantum cryptosystem standards being finalized and various countries issuing directives to switch to postquantum or at least ...
Chun-Ming Chiu, Jiaxiang Liu, Ming-Hsien Tsai, Xiaomu Shi, Bow-Yaw Wang, Bo-Yin Yang   +5 more
doaj   +1 more source

On Nonnegative Integer Matrices and Short Killing Words

, 2019
Let $n$ be a natural number and $\mathcal{M}$ a set of $n \times n$-matrices over the nonnegative integers such that the joint spectral radius of $\mathcal{M}$ is at most one. We show that if the zero matrix $0$ is a product of matrices in $\mathcal{M}$,
Kiefer, Stefan, Mascle, Corto
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source