Results 221 to 230 of about 4,310,333 (286)

31P Solid‐State NMR‐Enabled Development of a Pt/Aluminum Tripolyphosphate Catalyst for Selective C─O Bond Hydrogenolysis of Phenols

open access: yesAngewandte Chemie, EarlyView.
31P solid‐state nuclear magnetic resonance analysis revealed the presence of aluminum tripolyphosphate on the surface of a platinum/aluminum condensed phosphate mixture (ACPM) catalyst. This finding led to the development of a Pt/aluminum tripolyphosphate (Pt/ATPP) catalyst for the selective hydrogenolysis of phenols to arenes.
Kento Oshida   +11 more
wiley   +1 more source

Characterization of Full‐Length Antibody Complexes Through HDX‐Mass Spectrometry Coupled With NMR Spectroscopy: New Insight Into Avelumab/PD‐L1 Interaction

open access: yesAngewandte Chemie, EarlyView.
Combining HDX‐MS and NMR enables the mapping of epitopes and paratopes in full‐length antibody complexes, revealing transient interactions and potential artifacts. ABSTRACT Recombinant biomacromolecules have significantly transformed pharmaceuticals, in particular monoclonal antibodies (mAbs) that target key areas in oncology, immunology, inflammation,
Francesca Sacco   +13 more
wiley   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

open access: yesAngewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar   +2 more
wiley   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

open access: yesAngewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao   +8 more
wiley   +1 more source

Solvent‐Induced Structural Modulation in Nanoscale Covalent Organic Frameworks Enables High‐Performance NO2 Sensing

open access: yesAngewandte Chemie, EarlyView.
Solvent intercalation disrupts the stacking order of protonated porphyrin‐based 2D COF nanoparticles, resulting in a less compactly packed structure with increased accessibility of porphyrin sites. This structural modulation leads to significantly enhanced chemiresistive NO2 sensing performance.
Yu Pan   +4 more
wiley   +1 more source

Hyposmia in Parkinson's disease; exploring selective odour loss. [PDF]

open access: yesNPJ Parkinsons Dis
Mitchell E   +6 more
europepmc   +1 more source

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