Results 51 to 60 of about 45,762 (323)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Static Code Analysis: A Tree of Science Review

Entre Ciencia e Ingeniería, 2023
Static Code Analysis (SA) is the process of finding vulnerabilities in software. This process has become popular and one of the most evaluated phases in the process of continuous integration of software.
Gustavo Adolfo Ruiz, Sebastian Robledo Giraldo, Huber Hernando Morales   +2 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

Automatic Human-Like Detection of Code Smells

, 2021
Many code smell detection techniques and tools have been proposed, mainly aiming to eliminate design flaws and improve software quality. Most of them are based on heuristics which rely on a set of software metrics and corresponding threshold values. Those techniques and tools suffer from subjectivity issues, discordant results among the tools, and the ...
Chitsutha Soomlek, Jan N. van Rijn, Marcello M. Bonsangue   +2 more
openaire   +3 more sources

Removing Homocoupling Defects in Alkoxy/Alkyl‐PBTTT Enhances Polymer:Fullerene Co‐Crystal Formation and Stability

Advanced Functional Materials, EarlyView.
PBTTT‐OR‐R, a C14‐alkoxy/alkyl‐PBTTT polymer derivative, is of substantial interest for optoelectronics due to its specific fullerene intercalation behavior and enhanced charge‐transfer absorption. Comparing this polymer with (S) and without (O) homocoupling defects reveals that PBTTT‐OR‐R(O) forms stable co‐crystals with PC61BM, while PBTTT‐OR‐R(S ...
Zhen Liu, Jochen Vanderspikken, Paola Mantegazza, Stefania Moro, Mouna Hamid, Sigurd Mertens, Niko Van den Brande, Laurence Lutsen, Vincent Lemaur, David Beljonne, Giovanni Costantini, Koen Vandewal, Bruno Van Mele, Wouter Maes, Bart Goderis   +14 more
wiley   +1 more source

Is fat the sixth taste primary? Evidence and implications [PDF]

, 2015
Explores our tongue\u27s ability to detect fat as a distinct taste similar to our ability to sense sweet, sour, bitter, acid and savory. Abstract Taste is the chemical sense responsible for the detection of non-volatile chemicals in potential foods. For
Andrew Costanzo, Russell Keast
core   +1 more source

Mining Version Histories for Detecting Code Smells

IEEE Transactions on Software Engineering, 2015
Code smells are symptoms of poor design and implementation choices that may hinder code comprehension, and possibly increase change- and fault-proneness. While most of the detection techniques just rely on structural information, many code smells are intrinsically characterized by how code elements change over time.
PALOMBA, FABIO, G. Bavota, M. Di Penta, R. Oliveto, D. Poshyvanyk, DE LUCIA, Andrea   +5 more
openaire   +1 more source

Exploring Dipolar Dynamics and Ionic Transport in Metal‐Organic Frameworks: Experimental and Theoretical Insights

Advanced Functional Materials, EarlyView.
In this study, the interplay of dipolar dynamics and ionic charge transport in MOF compounds is investigated. Synthesizing the novel structure CFA‐25 with integrated freely rotating dipolar groups, local and macroscopic effects, including interactions with Cs cations are explored.
Ralph Freund, Arthur Schulz, Peter Lunkenheimer, Maryana Kraft, Thomas Bergler, Harald Oberhofer, Dirk Volkmer   +6 more
wiley   +1 more source

An Approach Based on Sum Product Networks for Code Smells Detection

Journal of Communications Software and Systems
From a software engineering perspective, a code smell refers to poor code structure. Many studies have shown that there is a significant negative relationship between code smells and code quality.
Mostefai Abdelkader
doaj   +1 more source