Results 101 to 110 of about 6,115,170 (308)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Bangla-English code-switching on Facebook: features and frequency

open access: yes, 2022
Access to thesis permanently restricted.The study examines the features of Bangla-English code-switching in language use in the social medium Facebook by Bangla speakers of Bangladesh, suggestive of the frequency of code-switching, types of code ...
Mow, Nilima Hakim
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Functions of code switching in multilingual classrooms

open access: yesPer Linguam : A Journal of Language Learning, 2011
The research reported in this paper focuses on the functions of code switching between English and Afrikaans in the classroom interactions of a secondary school in the Western Cape.
Ondene van Dulm, Suzanne Rose
doaj   +1 more source

Teachers’ and students’ attitudes and practices regarding code switching in writing: A study in selected primary schools in St. Lucia. [PDF]

open access: yes, 2011
This study was conducted in three primary schools in St. Lucia, a multilingual country situated in the Caribbean. The goal of this research was to investigate teachers’ and students’ attitudes and practices regarding the use of code switching in the ...
Auguste-Walter, Berthina
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

CODE-SWITCHING-ul ŞI CODE-MIXING-ul – CONSECINŢE ALE BILINGVISMULUI DIGLOSIC

open access: yesStudia Universitatis Moldaviae: Stiinte Umanistice, 2022
Code-switching is the practice of moving between variations of languages in different contexts. There are a number of possible reasons for the switching from one language to another. There are different perspectives on code-switching (social motivations/
USM ADMIN
doaj  

Analysis of Code Switching in Dialogue of Indonesian Novel Permainan Maut by Lexie Xu

open access: yesHumanis, 2019
This undergraduate thesis entitled “Analysis of Code Switching in Dialogue of Indonesian Novel Permainan Maut by Lexie Xu” has two aims which are; to analyze the types of code switching and the functions of code switching that is found in the novel.
Ni Putu Diana Yosi, I Gede Sadia
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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